Evidence map›Paper›PMID 42087559›Full record

ArticleBrain and behavior2026

Moderating Role of Psychological Flexibility in the Relationship Between Intolerance of Uncertainty and Perceived Stress Among Women Undergoing in Vitro Fertilization Treatment.

Fatemeh Karimzadeh, Abbas Abdollahi, Soolmaz Dehghanidowlatabadi

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Article in Brain and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Fatemeh KarimzadehDepartment of Counseling, Faculty of Education and Psychology, Alzahra University, Tehran, Iran.
Abbas AbdollahiWellbeing Research Center, UCSI University, Kuala Lumpur, Malaysia.
Soolmaz DehghanidowlatabadiDepartment of Counseling, SR.C., Islamic Azad University, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to examine the moderating role of psychological flexibility (PF) in the relationship between intolerance of uncertainty (IU) and perceived stress (PS) among women undergoing in vitro fertilization (IVF) treatment.

methodsThis study used purposive sampling and included 204 participants. The measurement instruments were the Intolerance of Ambiguity Scale (IUS-12) developed by Carleton and colleagues (2007) for assessing IU, the Perceived Stress Scale (PSS-10) developed by Cohen and colleagues (1983) for evaluating PS, and the Multidimensional Psychological Flexibility Inventory (MPFI-60) developed by Rolffs and colleagues (2018) for assessing PF. A covariance-based structural equation modeling using AMOS (version 24) software to test the direct relationships and multi-group analysis was conducted to assess moderation effects of PF. FINDING: The findings indicated that IU and Psychological Inflexibility (PI) positively predicted PS (β = 0.16, p < 0.001), while PF negatively predicted it (β = -0.14, p < 0.001). Multi-group analysis revealed that in the low PF group, the association between IU and PS was significant, positive, and greater (β = 0.28, p < 0.001) than in the high PF group (β = 0.06, p = 0.13).

conclusionBoth variables, namely IU and PI, contribute to increased PS; however, PF moderates this relationship, indicating a protective role of PF in reducing PS among women undergoing IVF treatment.

Indexed as

Fertilization in VitroStress, PsychologicalSubjective StressAdultCognitive FlexibilityFemaleHumansUncertaintyintolerance of uncertaintyin vitro fertilizationperceived stresspsychological flexibility

Identifiers

PMID42087559
PMCPMC13145355

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