Evidence map›Paper›PMID 42087484›Full record

ReviewComprehensive Physiology2026

Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development.

Shoulong Xu, Yanjiao Huang, Chenyue Hu, Wenli Ding, Zhenwei Pu, Qiang Li, Zhiliang Xu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Comprehensive Physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shoulong XuHuman Anatomy Experimental Training Center, School of Basic Medical Science, Wannan Medical University, Wuhu, Anhui, China.
Yanjiao HuangHuman Anatomy Experimental Training Center, School of Basic Medical Science, Wannan Medical University, Wuhu, Anhui, China.
Chenyue HuHuman Anatomy Experimental Training Center, School of Basic Medical Science, Wannan Medical University, Wuhu, Anhui, China.
Wenli DingHuman Anatomy Experimental Training Center, School of Basic Medical Science, Wannan Medical University, Wuhu, Anhui, China.
Zhenwei PuHuman Anatomy Experimental Training Center, School of Basic Medical Science, Wannan Medical University, Wuhu, Anhui, China.
Qiang LiHuman Anatomy Experimental Training Center, School of Basic Medical Science, Wannan Medical University, Wuhu, Anhui, China.
Zhiliang XuDD&E Institute, School of Basic Medical Sciences, Wannan Medical University, Wuhu, Anhui, China.

Funding

the Outstanding Youth Scientific Research Program for Universities in Anhui Province 2024AH020014
6 · The paper itself

Abstract

Exposure to harmful environments during pregnancy and maternal nutritional status are key factors that affect offspring development; however, the underlying mechanisms of maternal-fetal interaction remain to be elucidated. In recent years, research on gut microbiota and epigenetics has provided new perspectives for understanding these mechanisms. This review systematically summarizes the potential mechanisms by which the maternal gut microbiota influences prenatal development from an epigenetic perspective. Furthermore, it discusses the role of personalized nutritional interventions in the prevention of non-communicable diseases during embryonic and fetal development, aiming to provide new insights and intervention targets for promoting healthy pregnancies and enabling early disease prevention.

Indexed as

embryonic and fetal developmentepigeneticsmaternal‐fetal interactionmaternal gut microbiotanutritional intervention

Identifiers

PMID42087484
PMCPMC13145322

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.