Evidence map›Paper›PMID 42087214›Full record

ArticleJournal of cardiothoracic surgery2026

Myocardial protection during surgery for infective endocarditis: retrospective, single center, risk-adjusted study.

Murat Mukharyamov, Tulio Caldonazo, Philine Fleckenstein, Sebastian Freiburger, Hristo Kirov, Mathias Pletz, Stefan Hagel, Jürgen Bogoviku, Sandesh Dinesh, Stefan Glöckner and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Murat Mukharyamov *Department of Cardiothoracic Surgery, Jena University Hospital, Friedrich Schiller University of Jena, Am Klinikum 1, 07747, Jena, Germany.
Tulio Caldonazo *Department of Cardiothoracic Surgery, Jena University Hospital, Friedrich Schiller University of Jena, Am Klinikum 1, 07747, Jena, Germany.
Philine FleckensteinDepartment of Cardiothoracic Surgery, Jena University Hospital, Friedrich Schiller University of Jena, Am Klinikum 1, 07747, Jena, Germany.
Sebastian FreiburgerDepartment of Cardiothoracic Surgery, Jena University Hospital, Friedrich Schiller University of Jena, Am Klinikum 1, 07747, Jena, Germany.
Hristo KirovDepartment of Cardiothoracic Surgery, Jena University Hospital, Friedrich Schiller University of Jena, Am Klinikum 1, 07747, Jena, Germany.
Mathias PletzInstitute of Infectious Diseases and Infection Control, Jena University Hospital, Friedrich Schiller University of Jena, Jena, Germany.
Stefan HagelInstitute of Infectious Diseases and Infection Control, Jena University Hospital, Friedrich Schiller University of Jena, Jena, Germany.
Jürgen BogovikuDepartment of Internal Medicine I: Cardiology, Angiology, Intensive Care Medicine, Jena University Hospital, Friedrich Schiller University of Jena, Jena, Germany.
Sandesh DineshDepartment of Internal Medicine I: Cardiology, Angiology, Intensive Care Medicine, Jena University Hospital, Friedrich Schiller University of Jena, Jena, Germany.
Stefan GlöcknerInstitute of Medical Microbiology, Jena University Hospital, Friedrich Schiller University of Jena, Jena, Germany.
Micha BanzDepartment of Internal Medicine IV: Gastroenterology, Hepatology, Infectious Diseases, Interventional Endoscopy), Jena University Hospital, Friedrich Schiller University of Jena, Jena, Germany.
Mahmoud DiabDepartment of Cardiac Surgery, Helios University Hospital Wuppertal, University of Witten/Herdecke, Wuppertal, Germany.
Torsten DoenstDepartment of Cardiothoracic Surgery, Jena University Hospital, Friedrich Schiller University of Jena, Am Klinikum 1, 07747, Jena, Germany. doenst@med.uni-jena.de.
IKARUS study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCurrent evidence does not support superiority of one cardioplegia type over another, but stems from low-risk populations. Therefore, we compared outcomes of multimorbid, high-risk infective endocarditis (IE) patients receiving Custodiol

methodsWe retrospectively analyzed 553 patients (mean EuroScore II 22.7 ± 21.1) who underwent surgery for IE between 2009 and 2023 and received either cold crystalloid (Custodiol

resultsIn the overall cohort, patients receiving Custodiol

conclusionsIn high-risk endocarditis patients warm blood cardioplegia may be superior to cold crystalloid, although differences did not reach statistical significance. However, propensity matching may not have accounted for all differences, which warrants further discussion and investigation.

Indexed as

Cardiac Surgical ProceduresCardioplegic SolutionsEndocarditisHeart Arrest, InducedFemaleHumansMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRetrospective StudiesCardioplegic SolutionsCardioplegiaInfective endocarditisMyocardial protection

Identifiers

PMID42087214
PMCPMC13151226

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.