Evidence map›Paper›PMID 42086973›Full record

ArticleAnnals of surgical oncology2026

Well-Differentiated Liposarcoma of the Psoas Muscle: A Distinct Anatomic Subset with Highly Favorable Outcomes.

William W Tseng, Francesco Barretta, Marco Fiore, Stefano Radaelli, Marco Baia, Alessandra Borghi, Chiara Colombo, Roberta Sanfilippo, Chiara Fabbroni, Silvia Stacchiotti and 8 more

Abstract read
In one paragraph

Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

William W TsengDivision of Surgical Oncology, Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA. wtseng@coh.org.
Francesco BarrettaUnit of Biostatistics for Clinical Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Marco FioreSarcoma Service, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Stefano RadaelliSarcoma Service, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Marco BaiaSarcoma Service, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Alessandra BorghiSarcoma Service, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Chiara ColomboSarcoma Service, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Roberta SanfilippoDepartment of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Chiara FabbroniDepartment of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Silvia StacchiottiDepartment of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Elena Di BlasiDivision of Pathology, IRCCS Istituto Europeo di Oncologia, Milan, Italy.
Claudia SangalliDepartment of Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Albina AllajbejDepartment of Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Carlo MorosiDepartment of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Andrea VanzulliDepartment of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Sandro PasqualiSarcoma Service, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Dario CallegaroSarcoma Service, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Alessandro GronchiSarcoma Service, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRetroperitoneal (RP) liposarcoma (LPS) is characterized by histologic subtype and grade. This study sought to define outcomes for a novel subset of well-differentiated (WD) RP LPS defined by anatomic location in the psoas muscle.

methodsData were reviewed for all patients with primary WD LPS who underwent curative-intent complete resection at our sarcoma referral center from March 2006 to September 2021. For the study patients, clinicopathologic data were summarized. Crude cumulative incidences of local recurrence (LR) and disease-specific death (DSD) were estimated.

resultsThe 254 patients who met the inclusion criteria were stratified by location of their tumor: 12 RP psoas patients (group A), 123 RP non-psoas patients (group B), and 119 extremity patients (group C). Tumor size was greater in groups A (median, 20.0 cm) and B (median, 25.0 cm) versus group C (median, 15.0 cm; standardized mean difference [SMD], 0.747). Four patients (33 %) in group A underwent concomitant resection of muscle or nerve. In group B, 120 patients (97.5 %) had at least one organ resected (SMD, 5.606). During a median follow-up period of 8.8 years, no LR occurred in group A. The 5-year incidence of LR was 16.3 % in group B and 2.9 % in group C (p < 0.001). No DSDs occurred in group A or C, whereas the 5-year incidence of DSD was 1.9 % in group B.

conclusionsIn psoas WD LPS, local control rates and survival are highly favorable after surgery and approximate those seen for patients with extremity disease. With further multicenter validation, a more conservative approach to management may be indicated for this anatomically defined subset of RP liposarcoma.

Indexed as

LiposarcomaNeoplasm Recurrence, LocalPsoas MusclesRetroperitoneal NeoplasmsAdultAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesSurvival RateLiposarcomaPsoasRetroperitoneal SarcomaWell- Differentiated

Identifiers

PMID42086973
PMCPMC13337796

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.