Trial reportEuropean journal of pediatrics2026
The effect of virtual reality and buzzy® on pain, fear, and anxiety during skin prick testing in children: a randomized controlled trial.
Trial report in European journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Virtual Reality and Buzzy Application on Pain, Fear and Anxiety During Prick Test in Children: Randomized Controlled Study
The Effect of Watching Cartoons and Using a Stress Ball on Fear, Anxiety, Pain, and Satisfaction During Allergy Testing in Children
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Skin prick testing (SPT), although minimally invasive, is frequently associated with procedural pain, fear, and anxiety in pediatric populations. This randomized controlled trial aimed to compare the effectiveness of immersive virtual reality (VR) and the Buzzy® device in reducing procedural distress during SPT. In this randomized pretest-posttest study, 90 children aged 7-10 years undergoing first-time SPT at a Turkish university hospital were randomly allocated to VR distraction (n = 30), Buzzy® (n = 30), or routine care (n = 30). Pain, fear, and state anxiety were assessed before and after the procedure using validated pediatric scales reported by children, parents, and researchers. Group differences were analyzed using one-way ANOVA and chi-square tests. A mixed-design ANOVA examined group-time effects with Bonferroni-adjusted comparisons. Statistical significance was set at p < .05. Groups were comparable at baseline (p > .05). Significant group-time effects were identified for pain (F: 27.06, p < .001, pη
conclusionBoth VR and Buzzy® were associated with reduced procedural distress during SPT, with VR showing greater reductions than Buzzy® in this study. These findings suggest that structured, nurse-led distraction interventions may be beneficial; however, further studies are needed to confirm these results across different clinical settings. The findings suggest that integrating structured, nurse-led distraction strategies, particularly immersive VR, may substantially enhance atraumatic, child-centered care in pediatric allergy settings. The trial was registered at ClinicalTrials.gov in NCT06443060 (12/04/2025). WHAT IS KNOWN: •VR and Buzzy® both reduced pain, fear, and anxiety during SPT. •Both interventions were safe and feasible in clinical practice. WHAT IS NEW: •VR was more effective than Buzzy® in reducing these outcomes. •Findings support nurse-led, structured distraction strategies in pediatric allergy settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.