Evidence map›Paper›PMID 42086602›Full record

ReviewNature communications2026

Knowledge preservation in the era of big science and AI: strategies for sustainable scientific research.

Penn F Rainford, Annalisa Occhipinti, Bo Wang, Susan Stepney, Claudio Angione, Suraj Verma, Lucia Marucci, Kieren Sharma, Sarah A Harris, Rudolf M Füchslin and 11 more

Abstract readReview
In one paragraph

Review in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Penn F RainfordDepartment of Computer Science, University of York, York, UK. penn.rainford@york.ac.uk.ORCID http://orcid.org/0000-0002-0552-2209
Annalisa OcchipintiSchool of Computing, Engineering and Digital Technologies, Teesside University, Middlesbrough, UK.ORCID http://orcid.org/0000-0001-6075-1496
Bo WangLaboratory of Pathology, Center for Cancer Research, National Institute of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-5815-6185
Susan StepneyDepartment of Computer Science, University of York, York, UK.ORCID http://orcid.org/0000-0003-3146-5401
Claudio AngioneSchool of Computing, Engineering and Digital Technologies, Teesside University, Middlesbrough, UK.ORCID http://orcid.org/0000-0002-3140-7909
Suraj VermaSchool of Computing, Engineering and Digital Technologies, Teesside University, Middlesbrough, UK.ORCID http://orcid.org/0000-0002-9684-0885
Lucia MarucciSchool of Engineering Mathematics & Technology, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-7553-6358
Kieren SharmaSchool of Engineering Mathematics & Technology, University of Bristol, Bristol, UK.ORCID http://orcid.org/0009-0000-0336-9944
Sarah A HarrisSchool of Mathematical and Physical Sciences, Sheffield University, Sheffield, UK.ORCID http://orcid.org/0000-0002-2812-1651
Rudolf M FüchslinZHAW School of Engineering, Forschungsschwerpunkt Applied Complex Systems Science, Winterthur, Switzerland.ORCID http://orcid.org/0000-0002-9296-5314
Edda KlippInstitute of Biology, Humboldt-Universität zu Berlin, Theoretical Biophysics, Berlin, Germany.ORCID http://orcid.org/0000-0002-0567-7075
Claire S GriersonSchool of Biological Sciences, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-4000-0975
Mathias S WeylandZHAW School of Engineering, Forschungsschwerpunkt Applied Complex Systems Science, Winterthur, Switzerland.ORCID http://orcid.org/0000-0001-6389-0029
Aalap MogreDepartment of Microbiology, Moyne Institute of Preventive Medicine, Trinity College Dublin, Dublin, Ireland.ORCID http://orcid.org/0000-0003-2410-7008
Harold FellermannSchool of Computing, Newcastle University, Newcastle-upon-Tyne, UK.ORCID http://orcid.org/0000-0001-5861-1945
Le Minh Thao DoanSchool of Computing, Engineering and Digital Technologies, Teesside University, Middlesbrough, UK.ORCID http://orcid.org/0000-0001-9656-7287
Ioana M GhermanSchool of Engineering Mathematics & Technology, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-4042-0435
Alice L B PyneSchool of Chemical, Materials and Biological Engineering, Sir Robert Hadfield Building, Sheffield, UK.ORCID http://orcid.org/0000-0002-2658-8987
Timothy J RudgeSchool of Computing, Newcastle University, Newcastle-upon-Tyne, UK.
Victor M V BerrellezaSchool of Mathematical and Physical Sciences, Sheffield University, Sheffield, UK.ORCID http://orcid.org/0000-0002-4809-6254
Thomas E GorochowskiSchool of Biological Sciences, University of Bristol, Bristol, UK. thomas.gorochowski@bristol.ac.uk.ORCID http://orcid.org/0000-0003-1702-786X

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 101182278EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 101130747EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 955625RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/Y006933/1RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/Y007638/1RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/Y01278X/1RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/S01876X/1RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/T026308/1RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/V027395/1+2RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/Y001613/1RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/Y014073/1Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 228670
6 · The paper itself

Abstract

Science is losing knowledge it cannot afford to lose. Negative results go unpublished, hard-won expertise walks out the door with departing researchers, and preservation efforts remain fragmented. The consequences are wasted resources, duplicated effort, and missed discoveries. In this perspective, we argue that the research community can act now by embracing alternative dissemination channels, improving documentation best practices, and building sustainable digital infrastructure. We envision moderated platforms for sharing null results and practical know-how, community-driven standards, and AI-powered tools that lower barriers to implementation. With coordinated effort, science can become more open, efficient, and resilient for future generations.

Identifiers

PMID42086602
PMCPMC13144403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.