Alkyne migratory functionalization via C(sp

Ming-Qiao Tang, Hao-Ran Xu, Xian-Xiao Chen, Jia-Jun Qiao, Yi-Ming Ma, Long Wang, Xiao-Song Xue, Zhi-Tao He

Abstract read

In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ming-Qiao Tang *State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai, China.

Hao-Ran Xu *State Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai, China.

Xian-Xiao ChenState Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0003-2274-6578

Jia-Jun QiaoState Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai, China.

Yi-Ming MaState Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai, China.

Long WangCollege of Materials and Chemical Engineering, Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials, China Three Gorges University, Yichang, China. wanglongchem@ctgu.edu.cn.ORCID http://orcid.org/0000-0001-7548-014X

Xiao-Song XueState Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0003-4541-8702

Zhi-Tao HeState Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai, China. hezt@sioc.ac.cn.ORCID http://orcid.org/0000-0003-2375-9557

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22122104National Natural Science Foundation of China (National Science Foundation of China) 22371292Natural Science Foundation of Zhejiang Province (Zhejiang Provincial Natural Science Foundation) LMS26B020009

6 · The paper itself

Abstract

Different from broadly studied metal walking strategy as a powerful way to realize remote C-H activation of alkenes, process for alkyne walking and functionalization remains unexplored. Similarly, alkyne hydrofunctionalization exclusively focuses on in situ transformation, while related remote protocol is unknown. Here we describe a proof-of-concept study on migratory alkyne functionalization. Three types of alkynes and two types of nucleophiles are adopted to realize the migratory hydroalkylation and hydroamination of alkynes with good stereocontrol, which also represents a potential route for the asymmetric activation of three continuous inert C(sp

Identifiers

PMID42086563

DOI10.1038/s41467-026-72695-z

PMCPMC13350813

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.