ArticleThe Laryngoscope2026
Structural Phenotype of High-Frequency Recurrent Facial Palsy.
Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Peripheral facial palsy: contemporary advances and unresolved debates in management from pathogenic mechanisms to tailored reconstruction.Frontiers in neurology · 2026Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesHigh-frequency recurrence of peripheral facial palsy suggests an underlying structural predisposition. We aimed to identify the anatomical phenotype associated with ≥ 3 recurrences using high-resolution CT (HRCT).
methodsWe retrospectively analyzed 63 patients with high-frequency recurrence (mean 3.5 episodes) and 62 normal controls. Four HRCT parameters were quantified: geniculate ganglion (GG) enlargement, labyrinthine segment (LS) constriction, intracanalicular bony exostosis, and greater superficial petrosal nerve (GSPN) thickening. Inter-parameter correlations were also evaluated.
resultsThe mean age at the first attack was young (22.1 years). Intracanalicular bony exostosis was identified as the most potent predictor of recurrence (39.7% vs. 9.7%; OR: 7.39, p < 0.001). GG enlargement and GSPN thickening were significantly more prevalent in the recurrent group (p < 0.01) and showed a strong positive correlation (ρ = 0.58, p < 0.001), supporting a retrograde inflammatory spread mechanism. Overall, 63.5% of the recurrent group exhibited at least one structural or secondary finding (p < 0.001).
conclusionHigh-frequency recurrent facial palsy is associated with a structural phenotype, where fixed bony constraints like exostosis exacerbate chronic secondary inflammatory changes in the GG and GSPN. Recognizing these features on HRCT may help predict individuals at risk for recurrence and assist in planning targeted surgical decompression. LEVEL OF EVIDENCE: 3:
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