Evidence map›Paper›PMID 42086340›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2026

Hepatitis B and C Prevention, Screening, and Diagnostic Services at HIV Treatment Sites: International Epidemiology Databases to Evaluate AIDS.

Mark H Kuniholm, Gad Murenzi, Niharika Samala, Evy Yunihastuti, Gilles Wandeler, H Nina Kim, Marie K Plaisy, Hugo Perazzo, Christella Twizere, Francesca Odhiambo and 22 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Mark H KuniholmDepartment of Epidemiology and Biostatistics, College of Integrated Health Sciences, University at Albany, State University of New Yor, Albany, NY.ORCID 0000-0002-0173-9806
Gad MurenziResearch for Development (RD Rwanda), Kigali, Rwanda.
Niharika SamalaDivision of Gastroenterology and Hepatology, Department of Medicine, Indiana University, Indianapolis, IN.
Evy YunihastutiFaculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.
Gilles WandelerDepartment of Infectious Diseases, Inselspital, Bern University Hospital, Universtiy of Bern, Switzerland.
H Nina KimDepartment of Medicine, University of Washington, Seattle, WA.
Marie K PlaisyNational Institute for Health and Medical Research (INSERM) UMR 1219, Research Institute for Sustainable Development (IRD) EMR 271, University of Bordeaux, Bordeaux Population Health Centre, Bordeaux, France.
Hugo PerazzoEvandro Chagas National Institute of Infectious Diseases -Oswaldo Cruz Foundation (INI/FIOCRUZ), Rio de Janeiro, Brazil.
Christella TwizereCentre National de Référence en matière de VIH/SIDA (CNR), Bujumbura, Burundi.
Francesca OdhiamboKenya Medical Research Institute, Centre for Microbiology Research, Research Care and Training Program, Nairobi, Kenya.
Rohan BopageWestern Sydney Sexual Health Centre, Western Sydney Local Health District, Australia.
Guy MuulaCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Vincent Lo ReDivision of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Albert MingaCentre Médical de Suivi des Donneurs de Sang (CNTS-CI), Abidjan, Cote D'Ivoire.
Alvaro López-IñiguezInstituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico City, Mexico.
Dominique M NsondeCentre de Traitement Ambulatoire, Brazzaville, Republic of Congo.
Charles KasoziMasaka Regional Referral Hospital, Masaka City, Uganda.
Dewi K WatiDepartment of Pediatrics, Faculty of Medicine, Universitas Udayana, Prof. Dr. I.G.N.G Ngoerah General Hospital, Bali, Indonesia.
Matthew P FoxDepartment of Epidemiology, Boston University, Boston, MA.
Gregory D KirkDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Eugene MessouCentre de Prise en charge, de Recherche et de Formation (CePReF) Yopougon-Attié, Abidjan, Cote d'Ivoire.
Carina CesarInvestigaciones Clínicas, Fundación Huésped, Buenos Aires, Argentina.
Peter V EbasoneClinical Research Education Networking and Consultancy (CRENC), Yaounde, Cameroon.
Helen ByakwagaMbarara ISS Clinic, Mbarara, Uganda.
Jeremy RossTREAT Asia, amfAR-The Foundation for AIDS Research, Bangkok, Thailand.
Cleophas ChimbeteteNewlands Clinic, Harare, Zimbabwe.
George A YendewaDivision of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH.
Antoine JaquetNational Institute for Health and Medical Research (INSERM) UMR 1219, Research Institute for Sustainable Development (IRD) EMR 271, University of Bordeaux, Bordeaux Population Health Centre, Bordeaux, France.
Regina C M SucciUniversidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina, Centro de Atendimento da Disciplina de Infectologia Pediátrica (CEADIPe), São Paulo, SP, Brazil.
Fernanda MaruriDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN; and.
Ellen BrazierInstitute for Implementation Science in Population Health, City University of New York, New York, NY.
IeDEA

Funding

North American AIDS Cohorts on Collaboration and Design (NAACCORD)U01AI069918 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Keri Nicole Althoff, RICHARD Douglas MOORE · 2006 to 2026
$65.2M
East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional ConsortiumU01AI069911 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Leslie Anne Enane, AGGREY SEMWENDERO SEMEERE · 2006 to 2026
$57.7M
Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
The Asia-Pacific HIV Research CollaborationU01AI069907 · NIAID · FOUNDATION FOR AIDS RESEARCH · PI ANNETTE H SOHN · 2006 to 2026
$44.8M
CCASAnet: Caribbean, Central and South America NetworkU01AI069923 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Pedro Enrique Cahn, Jessica L Castilho · 2006 to 2026
$41.6M
"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
WADA (West Africa Database on Antiretroviral Therapy) CollaborationU01AI069919 · NIAID · UNIVERSITY OF BORDEAUX II · PI Didier Koumavi Ekouevi, Antoine Jaquet · 2006 to 2026
$29.9M
Harmonist: A Scalable Toolkit for Standardizing and Coordinating Data Sharing Across International Research NetworksR24AI124872 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Stephany Norah Duda · 2016 to 2026
$12.5M
National Institute of Allergy and Infectious Diseases R24AI24872National Institute of Allergy and Infectious Diseases U01AI069907National Institute of Allergy and Infectious Diseases U01AI069911National Institute of Allergy and Infectious Diseases U01AI069918National Institute of Allergy and Infectious Diseases U01AI069919National Institute of Allergy and Infectious Diseases U01AI069923National Institute of Allergy and Infectious Diseases U01AI069924National Institute of Allergy and Infectious Diseases U01AI096299NIAID NIH HHS R24 AI124872NIAID NIH HHS U01 AI069907NIAID NIH HHS U01 AI069911NIAID NIH HHS U01 AI069918NIAID NIH HHS U01 AI069919NIAID NIH HHS U01 AI069923NIAID NIH HHS U01 AI069924NIAID NIH HHS U01 AI096299
6 · The paper itself

Abstract

backgroundPrevention, screening, and diagnostic services for hepatitis B virus (HBV) and hepatitis C virus (HCV) can prevent morbidity and mortality in people receiving HIV care. However, there is limited information about the availability of HBV and HCV services at HIV clinics globally.

methodsThe International epidemiology Databases to Evaluate AIDS (IeDEA) conducted surveys of service delivery and practices at participating HIV treatment centers from 7 regions. We used 2023 survey data to measure availability of HBV vaccination, HBV and HCV screening, HBV surface antigen (HBsAg), HBV DNA, HCV antibody, and HCV RNA testing. Multivariable logistic regression models were used to test associations of site characteristics with HBV and HCV services.

resultsHBV vaccination was available on-site at 67.7% of 204 HIV treatment sites. Screening for HBV and HCV at HIV care enrollment was reported by 72.1% and 50% of sites, respectively. HBsAg, HBV DNA, HCV antibody, and HCV RNA testing were available on-site at 77%, 47.6%, 61.8%, and 44.6% of sites, respectively. Sites serving predominately rural (vs. urban) populations were less likely to report on-site availability of HBV DNA [odds ratio (OR):0.07; 95% confidence interval: 0.01 to 0.68; P = 0.02], HCV antibody (OR = 0.18; 95% CI: 0.04 to 0.92; P = 0.04), and HCV RNA (OR = 0.10; 95% CI: 0.01 to 0.90; P = 0.04) testing.

conclusionLife-saving services such as HBV vaccination, HBsAg, and HCV antibody testing were available on-site at most HIV treatment sites participating in the IeDEA network. Lower availability at rural sites suggests that expansion of services is important to eliminate HBV and HCV as public health problems in people receiving HIV care.

Indexed as

Diagnostic ServicesHepatitis BHepatitis CHIV InfectionsMass ScreeningDatabases, FactualFemaleHepatitis B VaccinesHepatitis C AntibodiesHumansHepatitis B VaccinesHepatitis C Antibodiesdiagnostichepatitis B virushepatitis C virusHIVpreventionscreeningservices

Identifiers

PMID42086340
PMCPMC13334928

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.