Evidence map›Paper›PMID 42086322›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2026

Electrophysiological Brain Connectivity and Subjective States Evoked by Electrical Stimulation of the Human Mid-thalamus.

Sofia Pantis, Masaya Togo, Dian Lyu, Weichen Huang, Julian Quabs, Heejung Jung, Eric van Staalduinen, Lindsay Liu Yang, Aidan Chan, Mina Fedor and 3 more

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Sofia PantisLaboratory of Behavioral and Cognitive Neuroscience, Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, California 94304.ORCID https://orcid.org/0009-0004-7761-9095
Masaya TogoLaboratory of Behavioral and Cognitive Neuroscience, Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, California 94304.ORCID https://orcid.org/0000-0003-4780-0868
Dian LyuLaboratory of Behavioral and Cognitive Neuroscience, Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, California 94304.
Weichen HuangLaboratory of Behavioral and Cognitive Neuroscience, Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, California 94304.ORCID https://orcid.org/0000-0002-9679-1956
Julian QuabsLaboratory of Behavioral and Cognitive Neuroscience, Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, California 94304.
Heejung JungLaboratory of Behavioral and Cognitive Neuroscience, Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, California 94304.ORCID https://orcid.org/0000-0001-5839-1655
Eric van StaalduinenDepartment of Radiology/Neuroimaging and Neurointervention, Stanford School of Medicine, Palo Alto, California 94304.
Lindsay Liu YangDepartment of Radiology/Neuroimaging and Neurointervention, Stanford School of Medicine, Palo Alto, California 94304.
Aidan ChanLaboratory of Behavioral and Cognitive Neuroscience, Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, California 94304.
Mina FedorLaboratory of Behavioral and Cognitive Neuroscience, Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, California 94304.
Robert FisherDepartment of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, California 94304.
Vivek BuchDepartment of Neurosurgery, Stanford School of Medicine, Palo Alto, California 94304.ORCID https://orcid.org/0000-0003-1151-6128
Josef ParviziLaboratory of Behavioral and Cognitive Neuroscience, Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, California 94304 jparvizi@stanford.edu.ORCID https://orcid.org/0000-0001-8520-7948

Funding

Human Thalamus in Propagation of Temporal Lobe Seizures and Memory FormationR01NS137650 · NINDS · STANFORD UNIVERSITY · PI ROBERT SCOTT FISHER, Josef Parvizi · 2025 to 2026
$1.2M
NINDS NIH HHS R01 NS137650
6 · The paper itself

Abstract

Recent developments in intracranial EEG allow direct recordings from the human thalamus, offering new insight into thalamocortical relationships in the human brain. In this study, we applied direct intracranial electrical stimulation (iES) to the mid-thalamus, within or close to the mediodorsal nucleus, to examine its impact on conscious experience and causal brain connectivity in 30 patients with focal epilepsy (10 females, 128 sites; 4 ± 1 sites per patient). Applying 50 Hz stimulations (iES

Indexed as

ConsciousnessThalamusAdolescentAdultBrain MappingElectric StimulationElectroencephalographyEpilepsies, PartialFemaleHumansMaleMiddle AgedNeural PathwaysYoung Adultcorticothalamic connectivityintracranial electrical stimulationmediodorsal thalamusSEEGstereoelectroencephalographythalamocortical connectivity

Identifiers

PMID42086322
PMCPMC13233911

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.