Evidence map›Paper›PMID 42086295›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2026

Learning-based cognitive control in ADHD: a multicentric study.

Lisa Toffoli, Giulia Stefanelli, Fiorella Del Popolo Cristaldi, Gian Marco Duma, Massimiliano Pastore, Vincenza Tarantino, Malida Franzoi, Marilena Vecchi, Alberto Danieli, Federica Martinez and 4 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Lisa ToffoliDepartment of General Psychology - DPG, University of Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-1664-7744
Giulia StefanelliDepartment of General Psychology - DPG, University of Padova, Padova, Italy.
Fiorella Del Popolo CristaldiDepartment of General Psychology - DPG, University of Padova, Padova, Italy.
Gian Marco DumaScientific Institute IRCCS E. Medea, Conegliano (TV), Italy.
Massimiliano PastoreDepartment of Developmental Psychology and Socialisation - DPSS, University of Padova, Padova, Italy.
Vincenza TarantinoDepartment of Psychology, Educational Sciences and Human Movement, University of Palermo, Palermo, Italy.
Malida FranzoiScientific Institute IRCCS E. Medea, Conegliano (TV), Italy.
Marilena VecchiScientific Institute IRCCS E. Medea, Conegliano (TV), Italy.
Alberto DanieliScientific Institute IRCCS E. Medea, Conegliano (TV), Italy.
Federica MartinezScientific Institute IRCCS E. Medea, Conegliano (TV), Italy.
Agnes BlayeCentre de Recherche en Psychologie et Neuroscience (UMR 7077), Aix-Marseille Université & CNRS, Marseille, France.
Corentin GonthierNantes Université, Univ Angers, Laboratoire de psychologie des Pays de la Loire, LPPL, UR 4638, Nantes, France.
CALM‐1 Team
Giovanni MentoDepartment of General Psychology - DPG, University of Padova, Padova, Italy.

Funding

Ministero della Salute
6 · The paper itself

Abstract

backgroundLearning-based cognitive control (CC), the ability to adapt control strategies based on contextual regularities, has been studied in typically developing (TD) children but remains underexplored in children with attention deficit hyperactivity disorder (ADHD). This study investigates whether children with ADHD show intact learning-based CC and how it is affected by increased cognitive demands.

methodsIn a multicentric study, 7-14 years old children (145 ADHD [20F, mean = 10.4 ± 2.0], 97 TD [51F, mean = 10.4 ± 2.0]) completed two experimental tasks: a modified Flanker task and a cued go-noGo task. Both included a List-Wide Proportion Congruency (LWPC) manipulation to create different contextual predictability (mostly congruent/valid vs. half congruent/valid blocks). Reaction times (RTs) and accuracy were analyzed across blocks, and we also examined associations between task adaptation and neuropsychological (NPS) as well as questionnaire-based measures of CC, including inhibition, cognitive flexibility, working memory, and behavioral difficulties.

resultsChildren with ADHD showed similar LWPC effects to TD peers in the Flanker task, suggesting preserved learning-based CC in low-demand contexts. In the cued go-noGo task, which involved greater attentional and inhibitory demands, children with ADHD displayed less efficient modulation of RTs and reduced speed-accuracy trade-off adaptation compared to TD peers. A composite NPS score predicted task adaptation. No associations were found with parental questionnaires.

conclusionsLearning-based CC appears preserved in children with ADHD in simple contexts but is hindered under complex, multi-demand conditions. Neuropsychological performance may be a key mechanism underlying these group differences. These findings emphasize the need for ecologically valid paradigms and tailored interventions targeting complex CC challenges in ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityCognitive FlexibilityExecutive FunctionInhibition, PsychologicalLearningPsychomotor PerformanceAdolescentChildFemaleHumansMaleReaction TimeADHDdevelopmentFlanker taskgo‐noGoinhibitionLearning‐based cognitive control

Identifiers

PMID42086295
PMCPMC13535711

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