Evidence map›Paper›PMID 42085660›Full record

ArticleJMIR aging2026

A Novel Combined Audiovisual-Semantic Digital Tool for Early-Stage Cognitive Decline Detection: Development and Validation Study.

Qiwei Wu, Binyu Zhao, Zihao Zheng, Betsy Seah, Xueping Zhang, Jing Shao

Abstract readValidation Study
In one paragraph

Article in JMIR aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qiwei WuDepartment of Nursing, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Hushan Road 200, Yiwu, Zhejiang Province, China.ORCID http://orcid.org/0000-0001-5656-2262
Binyu ZhaoDepartment of Nursing, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Hushan Road 200, Yiwu, Zhejiang Province, China.ORCID http://orcid.org/0000-0001-5906-631X
Zihao ZhengDepartment of Nursing, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Hushan Road 200, Yiwu, Zhejiang Province, China.ORCID http://orcid.org/0009-0008-3824-244X
Betsy SeahAlice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID http://orcid.org/0000-0002-6048-2190
Xueping ZhangDepartment of Geriatric Psychiatry, The Seventh People's Hospital of Hangzhou, Mental Health Center of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.ORCID http://orcid.org/0009-0009-7287-6611
Jing ShaoDepartment of Nursing, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Hushan Road 200, Yiwu, Zhejiang Province, China.ORCID http://orcid.org/0000-0002-6744-5771

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dementia poses a significant public health challenge. Early detection is crucial for timely intervention but remains difficult in community settings, as many existing cognitive screening tools are either insufficiently sensitive to subtle decline or too burdensome for widespread use. Objective: This study aimed to develop and validate a novel combined audiovisual-semantic digital tool for rapid and acceptable community-based screening of cognitive decline in older adults. Methods: A total of 156 older adults completed 6 progressively complex task variants shifting from unimodal to multimodal stimuli and from basic to superordinate semantic categorization. Performance was measured using reaction time, accuracy, false alarms, and inverse efficiency. Diagnostic utility was assessed via logistic regression and receiver operating characteristic curve analysis, whereas qualitative interviews evaluated acceptability. Results: Task outcomes showed significant declines across the cognitive continuum from no cognitive impairment to mild cognitive impairment to dementia (P<.001). The integrated audiovisual-semantic condition at the basic categorization level reliably differentiated cognitive groups and achieved higher area under the curve values for distinguishing no cognitive impairment from cognitive impairment and mild cognitive impairment from dementia compared to basic-level tasks. Incorporating semantic processing enhanced diagnostic discrimination. Participant feedback was highly positive, with 48.7% (76/156) describing the tasks as "fun/interesting." Conclusions: The audiovisual-semantic integrated digital tool is a valid, well-accepted, and time-efficient instrument for cognitive screening in older adults. Its design, which increases cognitive load through multimodal and semantic integration, improves sensitivity to early decline, supporting its potential for practical community application.

Indexed as

Cognitive DysfunctionMass ScreeningSemanticsAgedAged, 80 and overDementiaDigital MediaEarly DiagnosisFemaleHumansMaleNeuropsychological TestsROC Curveaudiovisual integrationcognitive declinecommunity screeninggo/no-go tasksemantic categorizationworking memory

Identifiers

PMID42085660
PMCPMC13143155

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.