Evidence map›Paper›PMID 42085310›Full record

ArticleAmerican journal of respiratory and critical care medicine2026

Inhaled anti-thymic stromal lymphopoietin antibody fragment, ecleralimab, in severe asthma: A placebo-controlled, multicenter, double-blind, randomized, phase 2b clinical trial.

Alexander J Mackay, Christian Gessner, Horacio Budani, Steven Weinstein, Yasushi Fukushima, Erika A Zannou-Mantri, Ilias Stavropoulos, James M Felser, Keroles Nakhla, Peter D'Andrea and 2 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexander J MackayNovartis Pharma AG, Basel, Switzerland.
Christian GessnerDepartment of Clinical Immunology, University Hospital Leipzig, Leipzig, Germany.
Horacio BudaniRespiratory Area of the Foundation for Clinical Assistance and Research in Prevalent Diseases (FAICEP), Buenos Aires, Argentina.
Steven WeinsteinAllergy and Asthma Specialists Medical Group and Research Center, Huntington Beach, CA, United States.
Yasushi FukushimaFukuwa Clinic, Tokyo, Japan.ORCID 0000-0002-6148-215X
Erika A Zannou-MantriNovartis Pharmaceuticals Corporation, East Hanover, NJ, United States.
Ilias StavropoulosNovartis Ireland Limited, Dublin, Ireland.
James M FelserNovartis Pharmaceuticals Corporation, East Hanover, NJ, United States.
Keroles NakhlaNovartis Pharmaceuticals Corporation, East Hanover, NJ, United States.
Peter D'AndreaNovartis Pharmaceuticals Corporation, East Hanover, NJ, United States.
Xintong ChenNovartis Pharmaceuticals Corporation, East Hanover, NJ, United States.
Paul M O'ByrneDepartment of Medicine, McMaster University, Hamilton, ON, Canada.

Funding

Novartis Pharma AG
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaHuman TSLPLung function

Identifiers

PMID42085310
PMCPMC13322294

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.