Evidence map›Paper›PMID 42085284›Full record

ArticleAmerican journal of respiratory and critical care medicine2026

Challenges for predicting oxygen response in OSA.

Christian D Harding, Scott A Sands, Jeremy E Orr, Bradley A Edwards, Christina Finch, Breanna M Holloway, Robert L Owens, Atul Malhotra, Christopher N Schmickl

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christian D HardingDivision of Pulmonary, Critical Care, Sleep Medicine and Physiology, University of California, San Diego (UCSD), CA, United States.
Scott A SandsDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Jeremy E OrrDivision of Pulmonary, Critical Care, Sleep Medicine and Physiology, University of California, San Diego (UCSD), CA, United States.
Bradley A EdwardsSchool of Psychological Sciences, Monash University, Melbourne, VIC, Australia.ORCID 0000-0001-9383-1644
Christina FinchDivision of Pulmonary, Critical Care, Sleep Medicine and Physiology, University of California, San Diego (UCSD), CA, United States.
Breanna M HollowayDivision of Pulmonary, Critical Care, Sleep Medicine and Physiology, University of California, San Diego (UCSD), CA, United States.
Robert L OwensDivision of Pulmonary, Critical Care, Sleep Medicine and Physiology, University of California, San Diego (UCSD), CA, United States.
Atul MalhotraDivision of Pulmonary, Critical Care, Sleep Medicine and Physiology, University of California, San Diego (UCSD), CA, United States.
Christopher N SchmicklDivision of Pulmonary, Critical Care, Sleep Medicine and Physiology, University of California, San Diego (UCSD), CA, United States.

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
San Diego Clinical and Translational Research InstituteUL1TR000100 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2012 to 2015
$19.7M
Is Obstructive Sleep Apnea Important in the Development of Alzheimer's DiseaseR01AG063925 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2020 to 2024
$3.7M
Role of ventilatory drive in obstructive sleep apnea: An avenue for precision interventionR01HL168067 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Scott A Sands · 2023 to 2026
$3.5M
Understanding Biological and Lifestyle Contributions to Alzheimer's Disease Pathology and Clinical Profiles in Black Women: Defining Prevention Targets in High Risk GroupsR01AG077579 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SARAH BANKS, Erin elizabeth Sundermann · 2023 to 2026
$3.5M
Underlying mechanisms of obesity-induced obstructive sleep apneaR01HL148436 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Atul Malhotra · 2020 to 2026
$3.4M
A Novel Pharmacological Therapy for Obstructive Sleep ApneaR01HL146697 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SANDS, SCOTT A · 2019 to 2023
$3.4M
Sleep Apnea Endophenotypes: One Size Does Not Fit AllR01HL154926 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2021 to 2025
$3.3M
The cardiovascular consequences of sleep apnea plus COPD (Overlap syndrome)R01HL166485 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Atul Malhotra · 2023 to 2026
$3.1M
VentNet: A Real-Time Multimodal Data Integration Model for Prediction of Respiratory Failure in Patients with COVID-19R01HL157985 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, NEMATI, SHAMIM · 2022 to 2025
$2.9M
Developing a Diverse Next Generation of Leaders in Respiratory ScienceT32HL166127 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Laura Elise Crotty Alexander, Atul Malhotra · 2023 to 2026
$1.6M
Acetazolamide to Improve Clinically Important Outcomes in Obstructive Sleep Apnea Patients with a High Loop Gain EndotypeK23HL161336 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Christopher Nikolaus Schmickl · 2022 to 2026
$863k
American Heart AssociationAmerican Heart Association-American Stroke Association 940501Eric and Wendy Schmidt AI in Science Postdoctoral Fellowship 2037735/6NCATS NIH HHS UL1 TR000100NCATS NIH HHS UL1 TR001442NHLBI NIH HHS K23 HL151880NHLBI NIH HHS K23 HL161336NHLBI NIH HHS R01 HL146697NHLBI NIH HHS R01HL146697NHLBI NIH HHS R01 HL148436NHLBI NIH HHS R01 HL154926NHLBI NIH HHS R01 HL157985NHLBI NIH HHS R01 HL166485NHLBI NIH HHS R01 HL168067NHLBI NIH HHS R01HL168067NHLBI NIH HHS T32 HL166127NIA NIH HHS 1R01AG077579NIA NIH HHS R01 AG063925NIA NIH HHS R01 AG077579NIHNIH HHS K23HL151880NIH HHS K23HL161336NIH HHS UL1TR000100NIH HHS UL1TR001442
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42085284
PMCPMC13318216

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.