ArticleAnnals of Indian Academy of Neurology2026
Outcomes of Endovascular Treatment in Medically Refractory Cerebral Venous Thrombosis: A Prospective Observational Study.
Article in Annals of Indian Academy of Neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesCerebral venous thrombosis (CVT) accounts for <0.5%-3% of all strokes but is increasingly identified with the availability of advanced imaging. Standard anticoagulation therapy is effective in most cases; however, a subset of patients experience clinical deterioration despite optimal medical management. Endovascular treatment (EVT) has emerged as a potential rescue therapy, though evidence remains limited due to the absence of randomized controlled trials. We aimed to evaluate the efficacy and safety of EVT in severe, medically refractory CVT cases at a tertiary care center in central India.
methodsThis prospective study included 36 patients with severe CVT who underwent EVT over 30 months. Procedures included catheter-directed thrombolysis, mechanical thrombectomy, and balloon venoplasty. Clinical features, procedural details, and outcomes were recorded. Post-procedure outcomes were assessed using the modified Rankin Scale (mRS) at 3 months.
resultsDuring the study period, out of the total cases of CVT presented to our center, 22.7% underwent endovascular thrombectomy. Of the 36 patients, 89.3% were male, and the majority were younger than 30 years. Headache was a universal presenting symptom, followed by seizures (75%) and focal neurological deficits (58.3%). All patients underwent balloon venoplasty; 35% received adjunctive thrombolysis, and 21% underwent aspiration thrombectomy. Technical success was achieved in all cases. Median mRS improved significantly from 3.0 at baseline to 1.0 at 3 months ( P < 0.001). No major complications occurred. Right sigmoid sinus thrombosis was significantly associated with complications ( P = 0.041).
conclusionsEVT is a safe and effective rescue option for patients with CVT refractory to standard anticoagulation, leading to substantial neurological recovery. Larger multicenter studies are needed to refine patient selection and standardized treatment protocols.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.