Evidence map›Paper›PMID 42084898›Full record

ArticleGigaScience2026

SCSEQ: A web tool for analyzing single-cell RNA-seq data.

Shiyu Du, Pengcheng Sun, Li Shen, Jian He

Abstract read
In one paragraph

Article in GigaScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shiyu DuQingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China), Shandong Key Laboratory of Intelligent Oil & Gas Industrial Software, Qingdao 266580, China.
Pengcheng SunQingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China), Shandong Key Laboratory of Intelligent Oil & Gas Industrial Software, Qingdao 266580, China.
Li ShenState Key Laboratory of Systems Medicine for Cancer, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Jian HeState Key Laboratory of Systems Medicine for Cancer, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.ORCID 0000-0002-1426-7799

Funding

China University of Petroleum 1500-05Y23080001National Key Technologies Research and Development Program of China 2022YFD2101503National Science and Technology Major Project 2026ZD0623600
6 · The paper itself

Abstract

backgroundSingle-cell RNA sequencing has emerged as a powerful approach to reveal cellular heterogeneity within biological systems. With the continuous advancement of high-throughput sequencing technologies, studies are generating vast amounts of complex data, posing a significant challenge for researchers in effective data processing and analysis.

resultsTo address this issue, we developed SCSEQ, an interactive web-based bioinformatics analysis platform. This platform enables even users without programming expertise to conveniently process and analyze sequencing data. SCSEQ provides a comprehensive workflow encompassing data preprocessing, normalization, clustering, dimension reduction, differential expression analysis, cell type identification, and downstream analyses. The downstream analysis tasks include gene enrichment analysis, transcription factor analysis, cell-cell communication analysis, copy number variation detection, trajectory inference, and pan-cancer analysis. SCSEQ facilitates information transfer between different workflows, accepts various input formats, and generates graphical and tabular outputs. As a user-friendly platform, we enhance user experience through detailed parameter settings and dynamic interactions. This enables users to precisely regulate research processes and customize result figures. Additionally, we provide comprehensive user manuals to assist with parameter configuration and workflow execution.

conclusionsSCSEQ provides an intuitive and convenient solution for single-cell transcriptome sequencing data analysis. Our platform has successfully completed full-process analyses on real-world data with reliable results, demonstrating its applicability in practical scenarios. The platform is available at https://scseq.com.cn/.

Indexed as

Computational BiologyRNA-SeqSequence Analysis, RNASingle-Cell AnalysisSoftwareGene Expression ProfilingHigh-Throughput Nucleotide SequencingHumansInternetSingle-Cell Gene Expression Analysisdata analysis platformmachine learningsingle-cell RNA sequencingweb-based tool

Identifiers

PMID42084898
PMCPMC13142160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.