Evidence map›Paper›PMID 42084713›Full record

ArticleUpdates in surgery2026

Ablation of cystic thyroid nodules with or without the injection of ethanol prior to aspiration: a one-year follow-up study.

Lorenzo Scappaticcio, Nicole Di Martino, Pamela Ferrazzano, Silvia Angelino, Michela Di Nuzzo, Miriam Longo, Alessandro Monaco, Giovanni Docimo, Maria Ida Maiorino, Katherine Esposito and 1 more

Abstract read
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Article in Updates in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lorenzo ScappaticcioDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, 80138, Italy. lorenzo.scappaticcio@unicampania.it.ORCID http://orcid.org/0000-0003-2972-9551
Nicole Di MartinoUnit of Endocrinology and Metabolic Diseases, AOU University of Campania "Luigi Vanvitelli", Naples, 80138, Italy.
Pamela FerrazzanoDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, 80138, Italy.
Silvia AngelinoDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, 80138, Italy.
Michela Di NuzzoDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, 80138, Italy.
Miriam LongoDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, 80138, Italy.
Alessandro MonacoUnit of Thyroid Surgery, AOU University of Campania "Luigi Vanvitelli", Naples, 80131, Italy.
Giovanni DocimoUnit of Thyroid Surgery, AOU University of Campania "Luigi Vanvitelli", Naples, 80131, Italy.
Maria Ida MaiorinoDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, 80138, Italy.
Katherine EspositoDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, 80138, Italy.
Giuseppe BellastellaDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, 80138, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the efficacy of ethanol ablation (EA) in treatment of cystic thyroid nodules (CTNs), according to procedure [with, contrariwise EA (contrEA), or without, classical (classEA), the injection of ethanol prior to aspiration] and injected ethanol amounts. We retrospectively reviewed consecutive patients treated with single-session EA for cytologically benign and symptomatic CTNs over four years. A total of 109 nodules were included [contrEA (n = 20) and classEA (n = 89)]. Twelve months after EA, median VRR was significantly higher in classEA group (93.1%) than contrEA (85.7%), while local symptoms did not significantly differ. Only the monolocular aspect of nodules could predict achievement of the three high efficacy outcomes (i.e., VRR > 75%, overall VAS score = 0, CS = 1), regardless of ethanol injected, EA procedure, nodule volume. EA, with or without the injection of ethanol prior to aspiration, is effective and positively influenced by the monolocular aspect of thyroid nodules, regardless of the EA procedure.

Indexed as

Efficacy outcomesEthanol ablationNodule volumeThyroid nodule

Identifiers

PMID42084713

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.