Evidence map›Paper›PMID 42084574›Full record

ArticleJACC. Case reports2026

Sinus Node Dysfunction in Takotsubo Syndrome: An Uncommon Presentation.

Georgios E Zakynthinos, Konstantinos Kalogeras, Georgios J Vlachojannis, George Makavos, Nikolaos K Kokkinos, Nektarios Souvaliotis, Efstratios Katsianos, Nikolaos Vythoulkas-Biotis, Polychronis Dilaveris, Gerasimos Siasos

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Georgios E ZakynthinosThird Department of Cardiology, "Sotiria" Chest Diseases Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: gzakynthinos2@gmail.com.
Konstantinos KalogerasThird Department of Cardiology, "Sotiria" Chest Diseases Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Georgios J VlachojannisThird Department of Cardiology, "Sotiria" Chest Diseases Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
George MakavosThird Department of Cardiology, "Sotiria" Chest Diseases Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Nikolaos K KokkinosThird Department of Cardiology, "Sotiria" Chest Diseases Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Nektarios SouvaliotisThird Department of Cardiology, "Sotiria" Chest Diseases Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Efstratios KatsianosThird Department of Cardiology, "Sotiria" Chest Diseases Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Nikolaos Vythoulkas-BiotisThird Department of Cardiology, "Sotiria" Chest Diseases Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Polychronis DilaverisThird Department of Cardiology, "Sotiria" Chest Diseases Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Gerasimos SiasosThird Department of Cardiology, "Sotiria" Chest Diseases Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStress cardiomyopathy is an acute, usually reversible left ventricular (LV) systolic dysfunction often triggered by emotional or physical stress. Conduction system complications are uncommon. CASE SUMMARY: A 68-year-old patient presented with acute pulmonary edema, reduced LV ejection fraction, and troponin elevation. Coronary angiography excluded obstructive coronary artery disease, and cardiac magnetic resonance confirmed stress cardiomyopathy. During hospitalization, the patient developed sinus node dysfunction (SND). Despite complete recovery of LV systolic function, the conduction abnormality persisted, requiring permanent pacemaker implantation. DISCUSSION: Arrhythmias occur in up to one-quarter of patients with stress cardiomyopathy, most commonly atrial fibrillation or ventricular arrhythmias, whereas persistent SND is rare. This case highlights that recovery of ventricular systolic function does not necessarily indicate recovery of conduction abnormalities and underscores the need for careful rhythm monitoring and individualized pacing decisions. TAKE-HOME MESSAGE: Persistent SND may complicate stress cardiomyopathy and may require permanent pacemaker implantation.

Indexed as

cardiac magnetic resonanceleft ventricleshortness of breathsupraventricular arrhythmiassystolic heart failure

Identifiers

PMID42084574
PMCPMC13261889

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.