ArticleTransplant infectious disease : an official journal of the Transplantation Society
Surgically Managed Deep Sternal Wound Infection After Heart Transplantation.
Article in Transplant infectious disease : an official journal of the Transplantation Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundDeep sternal wound infection (DSWI) remains a serious complication after heart transplantation (HT), yet data on its microbiology and outcomes are limited. We aimed to characterize the incidence, microbiology, management, and outcomes of DSWI after HT and to identify factors associated with its occurrence.
methodsWe retrospectively analyzed 298 consecutive HT recipients at a single tertiary center from 2010 to 2023. Patients were stratified by DSWI (n = 21, 7%) versus uncomplicated sternal healing (n = 277). Univariable and parsimonious multivariable logistic regression were used to assess factors associated with DSWI. Microbiologic findings among DSWI cases were described at the case level, including bacterial, fungal, and polymicrobial infections.
resultsDSWI cases had greater operative exposure, including longer graft ischemic time and cardiopulmonary bypass (CPB) duration. In multivariable analysis, ischemic time (adjusted OR: 1.008 min
conclusionsDSWI after HT was an infrequent but serious complication associated with worse long-term survival and greater operative burden. Microbiologic findings were heterogeneous, and pathogen-specific outcome patterns should be interpreted cautiously.
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