Evidence map›Paper›PMID 42084565›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society

Surgically Managed Deep Sternal Wound Infection After Heart Transplantation.

Jeng-Wei Chen, Heng-Wen Chou, Chuan-I Tsao, Nai-Kuan Chou, Chih-Hsien Wang, Nai-Hsin Chi, Shu-Chien Huang, Hsi-Yu Yu, Yih-Sharng Chen, Ron-Bin Hsu

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Article in Transplant infectious disease : an official journal of the Transplantation Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Jeng-Wei ChenDepartment of Surgery, National, Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan (ROC).
Heng-Wen ChouDepartment of Surgery, National, Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan (ROC).
Chuan-I TsaoDepartment of Surgery, National, Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan (ROC).
Nai-Kuan ChouDepartment of Surgery, National, Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan (ROC).
Chih-Hsien WangDepartment of Surgery, National, Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan (ROC).
Nai-Hsin ChiDepartment of Surgery, National, Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan (ROC).
Shu-Chien HuangDepartment of Surgery, National, Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan (ROC).
Hsi-Yu YuDepartment of Surgery, National, Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan (ROC).
Yih-Sharng ChenDepartment of Surgery, National, Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan (ROC).
Ron-Bin HsuDepartment of Surgery, National, Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan (ROC).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeep sternal wound infection (DSWI) remains a serious complication after heart transplantation (HT), yet data on its microbiology and outcomes are limited. We aimed to characterize the incidence, microbiology, management, and outcomes of DSWI after HT and to identify factors associated with its occurrence.

methodsWe retrospectively analyzed 298 consecutive HT recipients at a single tertiary center from 2010 to 2023. Patients were stratified by DSWI (n = 21, 7%) versus uncomplicated sternal healing (n = 277). Univariable and parsimonious multivariable logistic regression were used to assess factors associated with DSWI. Microbiologic findings among DSWI cases were described at the case level, including bacterial, fungal, and polymicrobial infections.

resultsDSWI cases had greater operative exposure, including longer graft ischemic time and cardiopulmonary bypass (CPB) duration. In multivariable analysis, ischemic time (adjusted OR: 1.008 min

conclusionsDSWI after HT was an infrequent but serious complication associated with worse long-term survival and greater operative burden. Microbiologic findings were heterogeneous, and pathogen-specific outcome patterns should be interpreted cautiously.

Indexed as

Heart TransplantationSternumSurgical Wound InfectionAgedFemaleHumansIncidenceMaleMediastinitisMiddle AgedRetrospective StudiesRisk Factorsfungal infectionheart transplantationmediastinitisoutcomesventricular assist device

Identifiers

PMID42084565
PMCPMC13450270

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.