Evidence map›Paper›PMID 42084443›Full record

ArticleEpilepsia2026

Developmental and cell type-specific contributions of thalamic serotonin 2A receptors to absence seizures.

Tatiana P Morais, Giulia Salamanca, Sandra H Vaz, Ana M Sebastião, Cristiano Bombardi, Vincenzo Crunelli, Giuseppe Di Giovanni

Abstract read
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In one paragraph

Article in Epilepsia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tatiana P MoraisNeuroscience Division, School of Bioscience, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0002-7486-9409
Giulia SalamancaDepartment of Veterinary Medical Science, University of Bologna, Bologna, Italy.ORCID https://orcid.org/0000-0003-4322-0030
Sandra H VazFaculdade de Medicina, Instituto de Farmacologia e Neurociências, Universidade de Lisboa, Lisbon, Portugal.ORCID https://orcid.org/0000-0003-4258-9397
Ana M SebastiãoFaculdade de Medicina, Instituto de Farmacologia e Neurociências, Universidade de Lisboa, Lisbon, Portugal.ORCID https://orcid.org/0000-0001-9030-6115
Cristiano BombardiDepartment of Veterinary Medical Science, University of Bologna, Bologna, Italy.ORCID https://orcid.org/0000-0002-5685-1977
Vincenzo CrunelliNeuroscience Division, School of Bioscience, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0001-7154-9752
Giuseppe Di GiovanniNeuroscience Division, School of Bioscience, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0003-2006-563X

Funding

Epilepsy Research UK P1202Ester Floridia Neuroscience Research Foundation 1502Horizon 2020 H2020-MSCA-ITN-2016Malta Council for Science and Technology (MCST) REP-2020-006UM Research Excellence Fund I20LU11Wellcome TrustWellcome Trust 91882
6 · The paper itself

Abstract

objectiveSerotonin 2A receptors (5-HT

methodsDouble-immunofluorescence labeling of 5-HT

resultsIn the VB, at postnatal day (P) 25, 5-HT SIGNIFICANCE: The developmental reorganization of thalamic 5-HT

Indexed as

AstrocytesEpilepsy, AbsenceNeuronsReceptor, Serotonin, 5-HT2AThalamusAnimalsElectroencephalographygamma-Aminobutyric AcidGlial Fibrillary Acidic ProteinMaleRatsgamma-Aminobutyric AcidGlial Fibrillary Acidic ProteinReceptor, Serotonin, 5-HT2Aastrocyteschildhood absence epilepsyGABA transporter 1thalamocortical neurons

Identifiers

PMID42084443
PMCPMC13525586

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.