Evidence map›Paper›PMID 42084382›Full record

ArticleApplied and environmental microbiology2026

Variations in cow milk and teat skin microbiota across the lactation cycle with intramammary cephalosporin use at dry-off.

Wannes Van Beeck, Mateus L P Lemos, Ashley M Niesen, Peter Finnegan, Taylor M Shih, Anhha Ho, Heidi A Rossow, Maria L Marco

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wannes Van BeeckDepartment of Food Science and Technology, University of California, Davis, California, USA.ORCID 0000-0003-0421-8931
Mateus L P LemosDepartment of Food Science and Technology, University of California, Davis, California, USA.
Ashley M NiesenVeterinary Medicine Teaching and Research Center, University of California, Davis, California, USA.ORCID 0000-0002-0587-6234
Peter FinneganDepartment of Food Science and Technology, University of California, Davis, California, USA.
Taylor M ShihDepartment of Food Science and Technology, University of California, Davis, California, USA.
Anhha HoDepartment of Food Science and Technology, University of California, Davis, California, USA.
Heidi A RossowVeterinary Medicine Teaching and Research Center, University of California, Davis, California, USA.ORCID 0000-0002-3753-4263
Maria L MarcoDepartment of Food Science and Technology, University of California, Davis, California, USA.ORCID 0000-0002-3643-9766

Funding

California Dairy Research Foundation P-21-007-UCD-MM-SR
6 · The paper itself

Abstract

Cephalosporins and other broad-spectrum antibiotics are frequently administered prophylactically into the udder when dairy cows end their lactation cycle, termed dry-off, to reduce mastitis risk. However, the use of antibiotics on cows that do not have signs of infection may result in the selection of antibiotic-resistant microorganisms and negatively alter the udder microbiome. In this study, the effects of intramammary cephalosporin therapy with Cephapirin (CB) or Ceftiofur (CH) on milk and teat skin microbiota were examined for three dairies in California. Intramammary injections were given to healthy cows with high somatic cell counts (>200,000 cells/mL), indicative of infection. Samples were collected at dry-off (before treatment), 7 days later, and 55-75 days in milk (DIM) in the next lactation cycle. Dairy (milk:

Indexed as

Anti-Bacterial AgentsCephalosporinsMammary Glands, AnimalMastitis, BovineMicrobiotaMilkSkinAnimalsBacteriaCattleCephapirinFemaleLactationSkin MicrobiomeThird Generation CephalosporinsAnti-Bacterial AgentsceftiofurCephalosporinsCephapirinThird Generation CephalosporinsantibioticsmastitismicrobiomemilkskinStaphylococcus

Identifiers

PMID42084382
PMCPMC13274448

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.