Evidence map›Paper›PMID 42084302›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2026

Does Total Inferior and Middle Turbinectomy Always Lead to Empty Nose Syndrome?

Nidhi Jha, Jed Speers, Ahmad Odeh, Zhenxing Wu, James Mihalich, Lauren E Gastineau, Bradley Hittle, Bradley A Otto, Kathleen M Kelly, Gregory J Wiet and 1 more

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In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nidhi JhaDepartment of Otolaryngology-Head & Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
Jed SpeersDepartment of Otolaryngology-Head & Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
Ahmad OdehDepartment of Otolaryngology-Head & Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
Zhenxing WuDepartment of Otolaryngology-Head & Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
James MihalichDepartment of Otolaryngology-Head & Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
Lauren E GastineauDepartment of Otolaryngology-Head & Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
Bradley HittleThe Department of Biomedical Informatics, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Bradley A OttoDepartment of Otolaryngology-Head & Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
Kathleen M KellyDepartment of Otolaryngology-Head & Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
Gregory J WietDepartment of Otolaryngology-Head & Neck Surgery, The Ohio State University, Columbus, Ohio, USA.
Kai ZhaoDepartment of Otolaryngology-Head & Neck Surgery, The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0003-4805-2689

Funding

Novel mechanisms and therapeutic approaches for nasal obstruction and olfactory lossesR01DC020302 · NIDCD · OHIO STATE UNIVERSITY · PI KAI ZHAO · 2022 to 2026
$2.0M
Endoscopic nasal sinus surgery simulator to optimize treatment outcomeR21DC017530 · NIDCD · OHIO STATE UNIVERSITY · PI ZHAO, KAI · 2019 to 2020
$442k
NIDCD NIH HHS R01 DC020302NIDCD NIH HHS R21 DC017530
6 · The paper itself

Abstract

objectiveEmpty Nose Syndrome (ENS) is a rare and paradoxical complication often associated with aggressive turbinate reductions. Previous computational fluid dynamic (CFD) modeling has indicated that distorted nasal airflow patterns could contribute to ENS. However, no data have shown that aggressive turbinate reductions consistently lead to ENS. STUDY

designRetrospective case series.

settingTertiary.

methodsWe retrospectively recruited 6 nasal obstruction patients who underwent turbinate reduction surgery, and performed total inferior and middle turbinectomies on all patients using a published virtual surgical simulator. We compared the CFD modeling results to that of patients' presurgery and postsurgery and published 27 ENS patients.

resultsAs expected, the virtual turbinectomy significantly expanded nasal airway cross-sectional area, more than that of actual surgery (inferior: 0.9 ± 0.4 to1.8 ± 0.3 cm

conclusionsENS cannot be solely attributed to aggressive turbinate reduction surgeries with various factors potentially playing a role.

Indexed as

Nasal ObstructionPostoperative ComplicationsTurbinatesAdultComputer SimulationFemaleHumansHydrodynamicsMaleMiddle AgedRetrospective StudiesSyndromeFESSfunctional endoscopic sinus surgeryturbinate hypertrophyturbinate reduction surgery

Identifiers

PMID42084302
PMCPMC13327433

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.