Evidence map›Paper›PMID 42084209›Full record

ArticleeLife2026

Hugin-AstA circuitry is a novel central energy sensor that directly regulates sweet sensation in

Wusa Qin, Tingting Song, Zeliang Lai, Daihan Li, Liming Wang, Rui Huang

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wusa Qin *Institute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen, China.
Tingting Song *Laboratory for Clinical Medicine, School of Public Health, Capital Medical University, Beijing, China.
Zeliang LaiCenter for Neurointelligence, School of Medicine, Chongqing University, Chongqing, China.
Daihan LiChinese Institutes for Medical Research, Beijing, China.
Liming WangInstitute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen, China.ORCID https://orcid.org/0000-0002-7256-8776
Rui HuangChinese Institutes for Medical Research, Beijing, China.

Funding

Guangdong Basic and Applied Basic Research Foundation 2023A1515110454National Natural Science Foundation of China 32071006National Natural Science Foundation of China 32271008
6 · The paper itself

Abstract

Taste sensation plays a crucial role in shaping feeding behavior and is intricately influenced by internal states like hunger or satiety. Despite the identification of numerous neural substrates regulating feeding behavior, the central neural substrate that linked energy-sensing and taste sensation remained elusive. Here, we identified a novel neural circuitry that could directly sense internal energy state and modulate sweet sensation in the

Indexed as

Drosophila melanogasterDrosophila ProteinsNeuropeptidesTasteAnimalsBrainDrosophilaGlucoseMiceNeuronsReceptors, G-Protein-CoupledReceptors, NeuropeptideallatostatinAstA-R1 protein, DrosophilaDrosophila ProteinsGlucoseHug protein, DrosophilaNeuropeptidesReceptors, G-Protein-CoupledReceptors, NeuropeptideAstAD. melanogasterfeedinghuginneurosciencesatietysweet sensation

Identifiers

PMID42084209
PMCPMC13143273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.