Evidence map›Paper›PMID 42083994›Full record

ArticleLiver international : official journal of the International Association for the Study of the Liver2026

Standardization of the Cirrhosis Admission Process and Its Impact on Inpatient Management and Patient Outcomes.

Laura E Lavette, Hannah Laird, Ashley Chipoletti, Mira Sridharan, Jessica J Dreicer, Andrew Barros, Zachary Henry

Abstract read
In one paragraph

Article in Liver international : official journal of the International Association for the Study of the Liver, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Standardization of the Cirrhosis Admission Process and Its Impact on Inpatient Management and Patient Outcomes.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laura E LavetteDepartment of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia, USA.ORCID 0009-0004-4987-526X
Hannah LairdDepartment of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Ashley ChipolettiDepartment of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Mira SridharanDepartment of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Jessica J DreicerDepartment of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Andrew BarrosDivision of Pulmonary and Critical Care, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Zachary HenryDivision of Gastroenterology and Hepatology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAn increase in cirrhosis-related hospitalizations has highlighted opportunities for improved patient care and standardization of practice. We created a cirrhosis admission order set with the goal of promoting guideline-directed care and improving patient outcomes.

methodsWe developed and implemented a cirrhosis order set that included dietary recommendations, diagnostic paracentesis orders and studies, common complications of portal hypertension and educational materials at time of discharge. We used a retrospective cohort design to compare post-intervention process measures and outcomes.

resultsThe use of the order set resulted in a significant increase in low sodium diet (93% vs. 37%, p = 0.001), high protein diet (91% vs. 37%, p = 0.001) and diagnostic paracentesis (46% vs. 26%, p = 0.001) performed during admission. There was also a significant reduction in time to diagnostic paracentesis (460 min vs. 1210 min, p = 0.03) and less all-cause Emergency Department visits (32% vs. 46%, p = 0.006) in the order set group. There was no significant impact on length of stay, readmission rates or in-hospital mortality. DISCUSSION: The use of a standardized order set improves inpatient management of cirrhosis and encourages guideline-directed care. This order set could easily be replicated at other institutions or among non-cirrhotic patient populations. Future work should focus on further standardization of the discharge process with the goal of having a more tangible impact on length of stay and readmission rates.

Indexed as

HospitalizationLiver CirrhosisPatient AdmissionAgedDiet, Sodium-RestrictedEmergency Room VisitsFemaleHumansHypertension, PortalLength of StayMaleMiddle AgedParacentesisPatient ReadmissionPractice Guidelines as TopicRetrospective Studiescirrhosisorder setquality improvement

Identifiers

PMID42083994
PMCPMC13140773

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.