Evidence map›Paper›PMID 42083927›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2026

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Paul Parcon, Mia Scrabis, Martin Nørgaard, Anthony Galassi, Paolo Zanotti-Fregonara, Jeih-San Liow, Robert B Innis, Min-Jeong Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paul ParconMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, USA.
Mia ScrabisMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, USA.
Martin NørgaardMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, USA.
Anthony GalassiMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, USA.
Paolo Zanotti-FregonaraMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, USA.
Jeih-San LiowMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, USA.
Robert B InnisMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, USA.
Min-Jeong KimMolecular Imaging Branch, National Institute of Mental Health, NIH, Bethesda, MD, USA.ORCID 0000-0002-0998-5972

Funding

PET Radiopharmaceutical SciencesZIAMH002793 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PIKE, VICTOR W · 2009 to 2025
$69.8M
Translational Evaluation Of PET RadiotracersZIAMH002795 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$32.0M
Intramural NIH HHS ZIA MH002793Intramural NIH HHS ZIA MH002795
6 · The paper itself

Abstract

Cyclooxygenase-1 (COX-1), an essential enzyme in the synthesis of pro-inflammatory prostanoids from arachidonic acid, is widely expressed in the brain, primarily in microglia. Previous studies from our laboratory found that the novel positron emission tomography (PET) radioligand [

Indexed as

AgingBrainCyclooxygenase 1Positron-Emission TomographyAdultAgedAge FactorsCarbon RadioisotopesClinical Trials, Phase I as TopicFemaleHumansMaleMiddle AgedObservational Studies as TopicYoung AdultCarbon-11Carbon RadioisotopesCyclooxygenase 1PTGS1 protein, humanAgingcyclooxygenase-1inflammationpositron emission tomographysex

Identifiers

PMID42083927
PMCPMC13144294

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.