Evidence map›Paper›PMID 42083919›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Barriers and Facilitators of Programmatic HPV Testing: Lessons Learnt From Two In-Depth Provincial Case Studies Ten Years After the Jujuy Demonstration Project in Argentina.

Melisa Paolino, Partha Basu, Eric Lucas, Mauricio Cucchiaro, Evangelina Melnik, Mariela Nieva, Natalia Martiarena, Marcelo Ríos, Rosa Laudi, Silvina Arrossi

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Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Melisa PaolinoCentro de Estudios de Estado y Sociedad/Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.ORCID 0000-0002-8649-1570
Partha BasuEarly Detection Prevention and Infections Branch, International Agency for Research on Cancer, Lyon, France.
Eric LucasEarly Detection Prevention and Infections Branch, International Agency for Research on Cancer, Lyon, France.
Mauricio CucchiaroPrograma de Prevención del Cáncer Cervicouterino, Dirección Provincial del Cáncer, Ministerio de Salud de Jujuy, San Salvador de Jujuy, Argentina.
Evangelina MelnikPrograma de Prevención del Cáncer Cervicouterino, Dirección Provincial del Cáncer, Ministerio de Salud de Catamarca, San Fernando del Valle de Catamarca, Argentina.
Mariela NievaDirección Provincial del Cáncer, Ministerio de Salud de Catamarca, San Fernando del Valle de Catamarca, Argentina.
Natalia MartiarenaPrograma de Prevención del Cáncer Cervicouterino, Dirección Provincial del Cáncer, Ministerio de Salud de Jujuy, San Salvador de Jujuy, Argentina.
Marcelo RíosPrograma de Prevención del Cáncer Cervicouterino, Dirección Provincial del Cáncer, Ministerio de Salud de Jujuy, San Salvador de Jujuy, Argentina.
Rosa LaudiHospital General de Agudos José María Ramos Mejía,Ministerio de Salud de la Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina.
Silvina ArrossiCentro de Estudios de Estado y Sociedad/Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionAchieving the global goal of cervical cancer elimination faces major challenges, particularly in ensuring the large-scale and sustained implementation of proven technologies. In Argentina, HPV testing as primary screening was introduced through the Jujuy Demonstration Project (JDP) in 2012. The aim of this study is to analyze barriers and facilitators of the implementation of HPV testing in two provinces-Jujuy, and Catamarca-a decade after the JDP's completion.MethodsWe carried out a descriptive in-depth case study using a mixed-method approach, using qualitative and quantitative methods. Data were collected through participant observations in health services, semi-structured interviews with key informants, analysis of secondary sources, and program indicators. Barriers and facilitators were analyzed using an adapted Health System Framework focusing on four key dimensions: stewardship, organizational capacity, financing, and technology.ResultsRegarding stewardship, reduced technical support and monitoring from the National Program emerged as significant barrier. About financing, the most critical obstacle was the national interruption in the provision of HPV tests. Although both provinces have initiated procedures to purchase tests using provincial funds, this process was constrained by limited financial resources and competing priorities. Finally, regarding organizational capacity, challenges persisted in maintaining laboratory centralization, sustaining the offer of self-collection, and fully utilizing information systems for program monitoring. Facilitators related to stewardship included the stability of human resource in both provinces and the long-standing institutional recognition and leadership of provincial program staff. Sustained adherence to national guidelines and the existence of provincial resolutions were key enablers of continuity. In addition, acceptability of the technology remained high, with HPV testing continuing to be widely accepted in both provinces.ConclusionsOur findings reveal barriers and facilitators in the implementation ten years after JDP finalization, providing valuable lessons for scaling up HPV-based screening in national cancer control programs.

Indexed as

Early Detection of CancerHuman Papillomavirus VirusesMass ScreeningPapillomavirus InfectionsUterine Cervical NeoplasmsArgentinaFemaleHumansArgentinacervical cancerHPVimplementationscreening- health system framework

Identifiers

PMID42083919
PMCPMC13158511

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.