ArticleCureus2026
Combined Immunotherapy and Hepatic Resection in Cutaneous Melanoma Liver Metastases.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melanoma is an aggressive malignancy with a high risk of distant metastasis, including hepatic involvement, which is associated with poor prognosis. We report a patient initially diagnosed with stage IA melanoma who developed an isolated liver metastasis seven years later. Molecular analysis identified a TP53 mutation and PD-L1 expression ≥ 1%. Treatment with nivolumab achieved a sustained radiological and biochemical response over four years. Owing to favorable systemic control and resectable disease, surgical liver resection was performed. Follow-up demonstrated no evidence of recurrence. At 48 months after initiation of immunotherapy and 12 months after surgery, the patient remains alive and disease-free. This case supports the integration of immunotherapy and surgery in selected patients with metastatic melanoma to the liver and highlights the importance of multidisciplinary management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.