Evidence map›Paper›PMID 42083711›Full record

ArticleCureus2026

Hemolytic Anemia in Liver Disease: A Case of Spur Cell Anemia.

Hajar El Amri, Asmitha P Reddy, Waqas Azhar, Baqai Junaid

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hajar El AmriInternal Medicine, Southern Illinois University School of Medicine, Springfield, USA.
Asmitha P ReddyInternal Medicine, Southern Illinois University School of Medicine, Springfield, USA.
Waqas AzharHematology/Oncology, Southern Illinois University School of Medicine, Springfield, USA.
Baqai JunaidPathology and Laboratory Medicine, Springfield Memorial Hospital, Springfield, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spur cell anemia (SCA) is a rare but severe form of acquired hemolytic anemia seen in advanced cirrhosis and carries a poor prognosis in the absence of liver transplantation. We report the case of a middle-aged man with alcohol-related cirrhosis who developed profound anemia requiring recurrent transfusions. An extensive workup was performed to rule out other causes of anemia, including gastrointestinal bleeding, microangiopathic hemolytic anemia, and autoimmune hemolytic anemia. Peripheral smear confirmed the presence of acanthocytes, consistent with SCA. Given that he was not a transplant candidate, supportive transfusions were provided, but his condition deteriorated rapidly, and he died within one month of diagnosis. This case highlights the aggressive course of SCA in non-transplant candidates and underscores the need for further research into alternative therapies.

Indexed as

alcohol-related cirrhosisdisseminated intravascular coagulation (dic)hemolytic anemialiver diseasespurr cell anemia

Identifiers

PMID42083711
PMCPMC13135478

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.