Evidence map›Paper›PMID 42083697›Full record

ArticleCureus2026

Severe Tophaceous Gout After Decades of Progressive Disease: A Case Report.

Grant Weiderman, Nicholas C Jianu, Skye Karastury, Puneet Mann, Nicholas Lorenz, Alexandra Jianu, Douglas Walsh

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Grant WeidermanMedicine, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Nicholas C JianuMedicine, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Skye KarasturyMedicine, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Puneet MannMedicine, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, USA.
Nicholas LorenzMedicine, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Alexandra JianuMedicine, Kirk Kerkorian School of Medicine at University of Nevada, Las Vegas (UNLV), Las Vegas, USA.
Douglas WalshInternal Medicine, MCR Health, Palmetto, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tophaceous gout is a chronic, progressive manifestation of hyperuricemia characterized by urate crystal deposition in soft tissues and joints throughout the body. Although effective urate-lowering therapies exist, management can be challenging in patients with prior medical conditions such as renal insufficiency and chronic kidney disease. This often leads to medication intolerance with subsequent joint deformity and disability. Here, we present a 63-year-old man with severe, chronic tophaceous gout that has caused significant limitations. Despite years of treatment with various methods, this patient has yet to receive appreciable relief.

Indexed as

case reportchronic goutchronic kidney diseasefunctional impairmentgouty tophihyperuricemiamusculoskeletal disabilityrefractory gouttophaceous gouturate-lowering therapy

Identifiers

PMID42083697
PMCPMC13135716

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.