ArticleCureus2026
Suspected Pancreatic-Pleural Fistula Presenting With Massive Pleural Effusion Complicated by Fatal Re-expansion Pulmonary Edema.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 author.
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Abstract
Pancreatic-pleural fistula (PPF) and re-expansion pulmonary edema (RPE) are rare but potentially fatal complications of pancreatitis. This report describes a 31-year-old man with a history of recurrent alcohol-associated pancreatitis who presented with acute hypoxic respiratory failure due to a large pleural effusion. Chest tube drainage revealed amylase-rich fluid, highly suggestive of a PPF. Rapid drainage of a large volume of pleural fluid precipitated RPE, followed by rapid clinical deterioration and cardiac arrest. This case highlights the importance of recognizing suspected PPF as a cause of large pleural effusions and the need for cautious drainage to prevent life-threatening complications such as RPE. To date, the coexistence of PPF complicated by fatal RPE has rarely been reported.
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