ArticleJournal of genetics2026
Combined transcriptome and metabolome analyses reveal that galactose metabolism is vital for tobacco in response to low-nitrate stress.
Article in Journal of genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Nitrogen is a primary factor affecting the yield and quality of tobacco. Insufficient nitrogen results in poor tobacco output and poor leaf quality; in contrast, excessive nitrate can lead to delayed maturity and poor quality of cured tobacco leaves. To elucidate the molecular mechanism underlying the response of tobacco to low nitrogen, we conducted a multiomics analysis of tobacco plants treated with normal (7.5 mM) or low nitrogen (0.75 mM). Our results revealed that after 15 days of low-nitrate treatment, the plants exhibited stunted growth, yellowed leaves, and significant growth inhibition. The total nitrogen levels, and the activities of glutamine synthetase and nitrate reductase in the leaves also decreased significantly. Transcriptome analysis of the tobacco plants under low-nitrogen stress revealed 896 differentially expressed genes, with 404 genes upregulated and 492 genes downregulated in comparison with those in the control. Among the upregulated genes, the expression of
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