ArticleNano letters2026
Using Well-Defined DNA Nanostructures To Study the Influence of DNA Clustering and Presentation on SNA Cellular Uptake.
Article in Nano letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Design of Spherical Nucleic Acids: From Fast Synthesis to Structural Engineering.Biomolecules · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Spherical nucleic acids (SNAs) are examples of how nucleic acid structures can impact important biological functions. Herein, we explore how well-defined DNA nanostructures assembled on the surface of preformed SNAs can influence important processes like cellular uptake. Three different DNA nanostructures, which vary in clustering and/or topology, were studied with three different cell lines (NIH-3T3, HaCaT, RAW 264.7). All three structures exhibited higher cellular uptake than conventional SNAs, with one structure (TX motif SNA) exhibiting a 5-fold increase after 4 h of incubation. Increased DNA clustering and DNA crossover numbers correlate with enhanced Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.