ArticleJournal of feline medicine and surgery2026
Longitudinal comparison of serum pancreatic lipase activity and pancreatic lipase immunoreactivity with clinical signs in cats with suspicion of pancreatitis.
Article in Journal of feline medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
ObjectivesIt remains unclear whether pancreatic lipase immunoreactivity (PLI) and lipase activity similarly reflect clinical status and disease severity in cats with suspected pancreatitis. This retrospective cohort study aimed to directly compare their association with clinical disease severity over time.MethodsA total of 21 client-owned cats with a suspicion of pancreatitis were followed up over a median of 6 weeks (range 1-130). The median number of rechecks was two (range 1-9). Lipase activity (LIPC, Roche Diagnostics; reference interval [RI] 8-26 U/l) and PLI (Spec fPL; RI 0-4.4 µg/l) were measured at each examination and compared with the clinical status of cats expressed as a clinical disease activity score (CDAS).ResultsNo significant correlation between CDAS and either lipase assay was detected at the initial evaluation. During 50 follow-up visits, both lipase assays showed moderate correlations of similar magnitude with CDAS (lipase activity:
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