Evidence map›Paper›PMID 42083082›Full record

ArticleThe Pediatric infectious disease journal2026

Neonatal Inflammatory Profiles Associated With Perinatally Acquired Hepatitis C Viral Infection.

Stephanie A Fisher, Grecio J Sandoval, George R Saade, Brenna L Hughes, Uma M Reddy, Edward K Chien, Alan T N Tita, John M Thorp, Torri D Metz, Vishakha Sabharwal and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Pediatric infectious disease journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Stephanie A FisherFrom the Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.ORCID 0009-0006-5085-1163
Grecio J SandovalThe George Washington University Biostatistics Center, Washington, District of Columbia.
George R SaadeDepartment of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas.
Brenna L HughesDepartment of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Brown University, Providence, Rhode Island.
Uma M ReddyThe Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
Edward K ChienDepartment of Reproductive Biology, MetroHealth Medical Center-Case Western Reserve University, Cleveland, Ohio.
Alan T N TitaDepartment of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama.
John M ThorpDepartment of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Torri D MetzDepartment of Obstetrics and Gynecology, University of Utah Health Sciences Center, Salt Lake City, Utah.
Vishakha SabharwalDepartment of Pediatrics, Boston Medical Center, Boston, Massachusetts.
Hyagriv N SimhanDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.
Geeta K SwamyDepartment of Obstetrics and Gynecology, Duke University, Durham, North Carolina.
Kent D HeyborneDepartment of Obstetrics and Gynecology, University of Colorado Anschutz School of Medicine, Aurora, Colorado.
Baha M SibaiDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Science Center at Houston, Children's Memorial Hermann Hospital, Houston, Texas.
Lynn M YeeDepartment of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama.
Yasser Y El-SayedDepartment of Obstetrics and Gynecology, Stanford University, Stanford, California.
Brian M CaseyDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.
Samuel ParryDepartment of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania.
Mona PrasadDepartment of Obstetrics and Gynecology, The Ohio State University, Columbus, Ohio.
Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network

Funding

LOC-IMPAACT Leadership GroupPharmacokinetics and Safety of Remdesivir for Treatment of COVID-19 in Pregnant Women in the USUM1AI068632 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI Jennifer Jao, Sharon A Nachman · 2011 to 2026
$278.1M
Statistical and Data Management Center-Pediatric,Adolescent, and Maternal CTGUM1AI068616 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Sean Scott Brummel, Marlene Ann Cooper · 2011 to 2026
$155.6M
LC - IMPAACT Leadership GroupUM1AI106716 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Grace M Aldrovandi · 2014 to 2026
$47.2M
SARS-CoV-2 Vaccine Pregnancy RegistryU24HD036801 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI Rebecca Gersnoviez Clifton · 2021 to 2026
$39.2M
Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040485 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Noelia Milena Modad Zork · 2016 to 2026
$3.6M
NICHD Maternal Fetal Medicine Units NetworkUG1HD087192 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Lorraine Dugoff · 2016 to 2026
$3.6M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040544 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI Kelly S Gibson, Angela C. Ranzini · 2016 to 2026
$3.5M
Maternal-Fetal Medicine Units Network -- The Northwestern Study CenterUG1HD040512 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Lynn M Yee · 2016 to 2026
$3.4M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040500 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI DWIGHT J ROUSE · 2016 to 2026
$3.4M
UofU Maternal-Fetal Medicine Units (MFMU) Network: Clinical CentersUG1HD034208 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Torri D Metz · 2016 to 2026
$3.4M
NICHD Maternal Fetal Medicine Units NetworkUG1HD027915 · NICHD · OHIO STATE UNIVERSITY · PI Maged Costantine · 2016 to 2026
$3.3M
UNC MFMU: Advancing Perinatal Health via Definitive, Multi-Site Clinical StudiesUG1HD040560 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI John M Thorp · 2016 to 2026
$3.3M
NIAID NIH HHS UM1 AI068616NIAID NIH HHS UM1 AI068632NIAID NIH HHS UM1 AI106716NICHD NIH HHS HHSN275201800001CNICHD NIH HHS HHSN275201800001INICHD NIH HHS U24 HD036801NICHD NIH HHS UG1 HD027869NICHD NIH HHS UG1 HD027915NICHD NIH HHS UG1 HD034116NICHD NIH HHS UG1 HD034208NICHD NIH HHS UG1 HD040485NICHD NIH HHS UG1 HD040500NICHD NIH HHS UG1 HD040512NICHD NIH HHS UG1 HD040544NICHD NIH HHS UG1 HD040545NICHD NIH HHS UG1 HD040560NICHD NIH HHS UG1 HD053097NICHD NIH HHS UG1 HD068258NICHD NIH HHS UG1 HD068268NICHD NIH HHS UG1 HD068282NICHD NIH HHS UG1 HD087192NICHD NIH HHS UG1 HD087230
6 · The paper itself

Abstract

In this nested case-control study of infants with in utero hepatitis C exposure, we assessed 21 plasma cytokines/chemokines at age 2 months in 11 infants with perinatal transmission and 11 negative controls. Of 6 detectable biomarkers, cases exhibited higher plasma programmed death-ligand 1, a proposed marker of T-cell exhaustion that requires further evaluation, specifically in infants with perinatal hepatitis C infection.

Indexed as

CytokinesHepatitis CInfectious Disease Transmission, VerticalInflammationPregnancy Complications, InfectiousBiomarkersCase-Control StudiesChemokinesFemaleHumansInfantInfant, NewbornMalePregnancyBiomarkersChemokinesCytokineschemokinescytokineshepatitis C virusinflammationperinatal

Identifiers

PMID42083082
PMCPMC13245272

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.