ArticleInfectious agents and cancer2026
Absence of chlamydial infection in ocular adnexal MALT lymphoma based on next-generation sequencing.
Article in Infectious agents and cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesExtranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) arises in various extranodal sites and has been linked to chronic inflammation, often triggered by infectious agents. Ocular adnexal (OA) MALT lymphoma has been associated with Chlamydophila psittaci (C. psittaci) in some regions. This study aimed to investigate the involvement of pathogenic microorganisms, including C. psittaci, in OA-MALT lymphoma.
methodsDNA was extracted from 17 formalin-fixed, paraffin-embedded OA-MALT lymphoma samples. Next-generation sequencing was performed, and reads were analyzed with bioinformatic pipelines to detect non-human DNA, focusing on complete or partial genomes of known pathogenic microorganisms, including C. psittaci strain 6BC and other bacteria implicated in lymphomagenesis.
resultsMost sequencing reads mapped to the human genome. No complete or partial genomes of C. psittaci 6BC or other non-human pathogenic microorganisms were detected above background levels, and no consistent enrichment of microbial sequences was observed. DISCUSSION: These findings suggest that, unlike in some Western cohorts, infectious agents such as C. psittaci are unlikely to play a major etiologic role in Japanese OA-MALT lymphoma.
conclusionOur analysis suggests that infectious agents, including C. psittaci, may be not associated with OA-MALT lymphoma in Japan.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.