Evidence map›Paper›PMID 42082957›Full record

ArticleBMC health services research2026

Regional features in the treatment of Parkinson's disease in the Baltic States compared to Germany.

Paula Abola, Ligita Smeltere, Ruta Kaladyte Lokominiene, Georg Straeten, Karlheinz Reinfrank, Katrin Sikk, Pille Taba

Abstract readComparative Study
In one paragraph

Article in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paula AbolaDepartment of Clinical Research, University of Jamestown, 4190 26th Ave. S., Fargo, ND, 58104, USA. paula.abola@uj.edu.
Ligita SmeltereMovement Disorder Society of Latvia, Brivibas iela 234-44, Riga, LV-1012, Latvia.
Ruta Kaladyte LokominieneCenter of Neurology, Faculty of Medicine, Vilnius University, Siltnamiu g. 29, Vilnius, LT-04130, Lithuania.
Georg StraetenIndependent Researcher, Münster, Germany.
Karlheinz ReinfrankParkinson Verbund e.V, Barbara-Straße 15, 48529, Nordhorn, Germany.
Katrin SikkNeurology Centre, North Estonia Medical Centre, J. Sütiste tee 19, Tallinn, 13419, Estonia.
Pille TabaInstitute of Clinical Medicine, Faculty of Medicine, University of Tartu, L. Puusepa 8, Tartu (linn), Tartumaa, 50406, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's Disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms, alongside non-motor manifestations. In advanced stages, people with PD (PwP) require extensive support to maintain mobility and quality of life, creating substantial demand on healthcare and reimbursement systems. Reported prevalence varies across Europe, with Germany at 350 per 100,000, Estonia at 314 per 100,000, Lithuania at 265 per 100,000, and Latvia at 217 per 100,000. This study applies a structured, qualitative comparative policy mapping approach (a subtype of comparative policy analysis) to describe and compare how national reimbursement and service-delivery rules shape access to PD treatments in Latvia, Lithuania, and Estonia, using Germany as a high-resource comparator. Key constructs, including availability, accessibility, affordability, and reimbursement, were defined a priori and operationalized into extractable indicators (e.g., formulary inclusion, reimbursement rate, cost-sharing, authorization requirements, and service-capacity proxies). Data sources included reimbursement agency databases, national formularies, policy documents, and expert input. Analysis was structured across three domains: pharmacological therapy, device-assisted therapies (DATs), and rehabilitation and supportive therapies. Findings show that Germany ensures broad access to all treatment domains, including newer pharmacological options, reimbursed DATs, and structured multidisciplinary rehabilitation. Estonia and Lithuania provide full reimbursement for standard medications but limited access to DATs and variable rehabilitation services. Latvia remains most constrained, with partial reimbursement for medications, no reimbursed DATs, and underdeveloped supportive therapies. Differences in reimbursement design (including cost-sharing and eligibility rules) and service capacity co-occur with broader system financing differences (total health expenditure: 12.6% of GDP in Germany vs. 7.6% in Latvia, 7.2% in Lithuania, and 7.0% in Estonia; government-funded expenditure: 10.1%, 4.9%, 4.7%, and 5.2%, respectively). These findings are descriptive and intended to clarify where policy design and implementation may plausibly contribute to cross-country variation in access.

Indexed as

Health Services AccessibilityParkinson DiseaseAntiparkinson AgentsBaltic StatesGermanyHumansInsurance, Health, ReimbursementAntiparkinson AgentsBaltic StatesDevice-assisted therapiesGermanyParkinson’s diseasePharmacological treatmentsSupportive therapies

Identifiers

PMID42082957
PMCPMC13312687

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.