Evidence map›Paper›PMID 42082813›Full record

Observational studyEuropean journal of pediatrics2026

Risk factors for severe post-COVID condition in children, adolescents, and young adults.

Quirin Donath, Matthias Haegele, Daniela Schindler, Tiziana Welzhofer, Catharina Christa, Annika Grabbe, Ariane Leone, Clara Ilhan, Carola Weidmann, Maria Eberhartinger and 20 more

Abstract readObservational Study
In one paragraph

Observational study in European journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Quirin DonathTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Matthias HaegeleTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Daniela SchindlerTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Tiziana WelzhoferTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Catharina ChristaTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Annika GrabbeTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Ariane LeoneTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Clara IlhanTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Carola WeidmannTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Maria EberhartingerTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Sara BechtoldTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Child and Adolescent Psychosomatics, Children's Hospital, Munich, Germany.
Nicola BurschTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Child and Adolescent Psychosomatics, Children's Hospital, Munich, Germany.
Hedwig WolfTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Hannah HieberTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Laura-Carlotta PeoTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Lara A BuckaTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Silvia StojanovTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Child and Adolescent Psychosomatics, Children's Hospital, Munich, Germany.
Cordula WarlitzTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Martin AlbererTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Katrin GerrerTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Anna HausruckingerTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Kirstin MittelstrassTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Clemens-Martin WendtnerMedical Clinic III, Ludwig-Maximilians University (LMU), Munich, Germany.
Manuela A HoechstetterMedical Clinic III, Ludwig-Maximilians University (LMU), Munich, Germany.
Armin GrüblTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Nicole ToepfnerDepartment of Pediatrics, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Rafael PricocoTUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.
Carmen ScheibenbogenInstitute of Medical Immunology, Charité-Universitaetsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität Zu Berlin and Berlin Institute of Health (BIH), Berlin, Germany.
Lorenz L Mihatsch *TUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany. l.mihatsch@tum.de.
Uta Behrends *TUM School of Medicine and Health, Munich Chronic Fatigue Center for Young People (MCFC), Pediatrics, Children's Hospital, Technical University of Munich, Munich, Germany.

Funding

Bavarian State Ministry of Health and Care 2490-PCS-2023-V13, 2490-PC-2021-V6-D44360/2021
6 · The paper itself

Abstract

Post-COVID condition (PCC) in children and young people (CYP, PCCcyp) remains a significant health burden. Early identification of patients at risk for severe disease, including myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), is crucial for timely and adequate care. This monocentric, observational registry study, performed at a tertiary pediatric hospital in Germany, included CYP aged 7-25 years with PCCcyp at diagnosis. Standardized clinical assessment tools and patient-reported outcome measures were applied, including the novel Munich Long COVID Symptom Questionnaire (MLCSQ). Severe PCC was defined by chronic symptom clusters, Fatigue Severity Scale (FSS), Total Composite Autonomic Symptom Score-31 (COMPASS-31), SF-36 composite scores, Bell Score, and confirmed ME/CFS diagnosis. Among 120 participants, severe PCCcyp was associated with a higher number of acute symptoms (OR

Indexed as

COVID-19AdolescentAdultChildFatigue Syndrome, ChronicFemaleGermanyHumansMalePost-Acute COVID-19 SyndromeRegistriesRisk FactorsSARS-CoV-2Severity of Illness IndexSymptom BurdenYoung AdultLong COVIDMyalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)Post-acute sequelae of COVID-19 (PASC)Post-COVID-19 condition (PCC)Post-COVID syndrome (PCS)Post-exertional malaise (PEM)

Identifiers

PMID42082813
PMCPMC13139278

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.