Evidence map›Paper›PMID 42082789›Full record

ArticleJournal of patient-reported outcomes2026

Patient satisfaction following gender affirming facial surgery: a GENDER-Q and gender preoccupation and stability questionnaire study (GPSQ).

Helia C Hosseini, Thayer J Mukherjee, Paula Flores-Perez, Melanie Vassallo, Jacqueline Ihnat, Sasha Wood, Kevin Hu, Neil Parikh, Omar Allam, Michael Alperovich

Abstract read
In one paragraph

Article in Journal of patient-reported outcomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Helia C Hosseini *Division of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar Street, Boardman Building, New Haven, Connecticut, USA.
Thayer J Mukherjee *Division of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar Street, Boardman Building, New Haven, Connecticut, USA.
Paula Flores-PerezDivision of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar Street, Boardman Building, New Haven, Connecticut, USA.
Melanie VassalloDivision of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar Street, Boardman Building, New Haven, Connecticut, USA.
Jacqueline IhnatDivision of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar Street, Boardman Building, New Haven, Connecticut, USA.
Sasha WoodDivision of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar Street, Boardman Building, New Haven, Connecticut, USA.
Kevin HuDivision of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar Street, Boardman Building, New Haven, Connecticut, USA.
Neil ParikhDivision of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar Street, Boardman Building, New Haven, Connecticut, USA.
Omar AllamDivision of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar Street, Boardman Building, New Haven, Connecticut, USA.
Michael AlperovichDivision of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar Street, Boardman Building, New Haven, Connecticut, USA. Michael.alperovich@yale.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGender-affirming facial surgery (GAFS) addresses gender dysphoria by aligning facial features with gender identity, with historical emphasis on refining the upper facial third to render patients more attractive and feminine. The GENDER-Q, a novel patient-reported outcome measure (PROM), evaluates aesthetic, functional, and psychosocial outcomes, complementing the Gender Preoccupation and Stability Questionnaire (GPSQ) to assess effects of GAFS in this study. METHODOLOGY: Survey data from 86 patients was analyzed using GENDER-Q and GPSQ scores. Higher GENDER-Q scores indicated improved outcomes, whereas lower GPSQ scores reflected reduced gender dysphoria. Pre- and post-operative outcomes were compared using paired and unpaired t-tests. Spearman's correlation coefficients assessed relationships between the parameters assessed.

resultsSignificant improvements in post-operative GENDER-Q scores were observed across facial features, with upper face appearance (r = 0.54, p = 0.001), jaw (r = 0.49, p = 0.001), and chin (r = 0.48, p = 0.004), showing greatest gains. GPSQ scores decreased significantly (-7.77 ± 1.61, p < 0.001). Pre- to post-operative changes of dysphoria, as measured by the GENDER-Q were associated with overall face (r = 0.62, p < 0.001), upper face (r = 0.64, p < 0.001), and chin (r = 0.51, p = 0.08) score improvement. Furthermore, increased overall facial satisfaction strongly correlated with improvement in satisfaction with the upper face (r = 0.54, p = 0.001), jaw (r = 0.49, p = 0.001), and chin (r = 0.48, p = 0.004).

conclusionsAn individualized approach to gender-affirming facial surgery that prioritizes overall facial harmony, rather than isolated subunit changes, improves gender congruence, facial satisfaction, and alleviates gender dysphoria in transgender patients. In addition, this study advocates for the use of tailored PROMs for the transgender population to more precisely capture and quantify the impact of population-specific interventions and conditions such as gender-affirming surgery and gender dysphoria respectively.

Indexed as

FaceGender-Affirming SurgeryGender DysphoriaPatient Reported Outcome MeasuresPatient SatisfactionAdolescentAdultFemaleHumansMaleMiddle AgedSurveys and QuestionnairesYoung AdultGender-affirming facial surgeryGender dysphoriaGENDER-QPatient-reported outcomesTransgender health

Identifiers

PMID42082789
PMCPMC13315363

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.