Evidence map›Paper›PMID 42082749›Full record

ArticleEuropean journal of applied physiology2026

Position dependent elasticity of the anterior talofibular ligament in healthy young women: an in-vivo shear wave elastography study.

Zili Chen, Wan Zhou, Hao Liang, Xing Liu, Yibo Li, Li Yang, Huijuan Xiang, Rui Du

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Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Zili Chen *Department of Ultrasound, General Hospital of Central Theater Command, Wuhan, China.
Wan Zhou *Department of Ultrasound, General Hospital of Central Theater Command, Wuhan, China.
Hao LiangDepartment of Ultrasound, General Hospital of Central Theater Command, Wuhan, China.
Xing LiuDepartment of Health Examination, Wuhan Special Service Recuperation Center Chinese People's Armed Police Forces, Wuhan, China.
Yibo LiDepartment of Orthopedics, General Hospital of Central Theater Command, Wuhan, China.
Li YangDepartment of Ultrasound, General Hospital of Central Theater Command, Wuhan, China.
Huijuan XiangDepartment of Ultrasound, General Hospital of Central Theater Command, Wuhan, China.
Rui DuDepartment of Ultrasound, General Hospital of Central Theater Command, Wuhan, China. durui900@126.com.ORCID http://orcid.org/0000-0002-1307-4098

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe anterior talofibular ligament (ATFL) is the primary restraint to ankle inversion, yet quantitative in vivo data on its elastic behavior across functional positions are limited. Shear wave elastography (SWE) provides noninvasive estimates of local elastic parameters (surrogate indices of material stiffness rather than direct measures of structural stiffness). We aimed to characterize ATFL SWE-derived parameters in baseline position and examiner-assisted passive maximal-inversion position.

methodsIn this cross-sectional study, 50 healthy adult female volunteers (aged 20-39) underwent SWE of the dominant-side ATFL using a high-frequency linear transducer in musculoskeletal mode. Three 1 mm diameter circular regions of interest (proximal, middle, and distal) were assessed in both positions, and ATFL length was measured in each posture. Posture-dependent differences were tested with paired t-tests or Wilcoxon tests as appropriate. Associations between Shear wave velocity (SWV) and demographic variables were explored using Spearman's correlation.

resultsSWV increased significantly from the baseline to examiner-assisted passive maximal-inversion position at all sites (all P < 0.001), rising from 3.21 to 3.45 m/s to 4.04-4.68 m/s. ATFL length increased modestly from 17.0 ± 1.5 mm to 17.4 ± 1.5 mm (P < 0.017). No significant correlations were observed between SWV and age, height, body mass, BMI, or foot length (all P > 0.0017).

conclusionsIn healthy young women, ATFL SWE-derived elastic parameters increase in an examiner-assisted passive maximal-inversion position, consistent with greater mechanical engagement. These posture-specific reference values support future studies in ankle sprain and chronic ankle instability.

Indexed as

ElasticityElasticity Imaging TechniquesLateral Ligament, AnkleAdultAnkle JointCross-Sectional StudiesFemaleHumansPostureYoung AdultAnkle jointAnterior talofibular ligamentBiomechanical phenomenaUltrasound elastography

Identifiers

PMID42082749
PMCPMC13541848

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.