Evidence map›Paper›PMID 42082683›Full record

ArticleNPJ cardiovascular health2026

Pulse pressure associates with severity and worse outcomes in patients with stable coronary artery disease.

Yan Zhang, Sha Li, Hui-Wen Zhang, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Rui-Xia Xu, Jie Qian, Ke-Fei Dou, Jian-Jun Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ cardiovascular health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan ZhangCardiometabolic Center, State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Sha LiCardiometabolic Center, State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Hui-Wen ZhangCardiometabolic Center, State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Yuan-Lin GuoCardiometabolic Center, State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Na-Qiong WuCardiometabolic Center, State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Cheng-Gang ZhuCardiometabolic Center, State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Rui-Xia XuCardiometabolic Center, State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Jie QianCardiometabolic Center, State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. qianjfw@163.com.
Ke-Fei DouCardiometabolic Center, State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. doukefei@fuwaihospital.org.
Jian-Jun LiCardiometabolic Center, State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. lijianjun938@126.com.

Funding

CAMS Major Collaborative Innovation Project 2016-I2M-1-011Capital Health Development Fund 201614035
6 · The paper itself

Abstract

The association of pulse pressure (PP) with the severity and cardiovascular (CV) outcomes in stable coronary artery disease populations with normal ejection fraction are sparse. We enrolled 7,027 patients and follow-up 36.4 months, a total of 289 events occurred. Both systolic blood pressure (SBP) and PP were significantly increased by Gensini Score quartiles. Meanwhile, the percentage of 3-diseased vessels was increasing by PP quartiles (p < 0.001). On univariate analysis, both PP and SBP were associated with CV death, stroke, and combined outcome (p < 0.05, all). However, after adjusting for potential confounders, PP remains significantly associated with stroke (HR 95%CI 1.019[1.005-1.033]) and combined outcome (HR 95%CI 1.014[1.005-1.023]) while SBP was only associated with stroke (HR 95%CI 1.014[1.003-1.026]). On multivariate analysis, the highest PP quartile consistently associated with stroke and combined outcome (p < 0.05, all). This prospective cohort study suggesting that PP may be a pivotal predictor for CV risk.

Identifiers

PMID42082683
PMCPMC13139599

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.