Evidence map›Paper›PMID 42082614›Full record

ArticleEye (London, England)2026

OphthoEvidence: a model for rapid and trustworthy ophthalmology guidelines.

João Pedro Lima, Dena Zeraatkar, Marah Al Masri, Sobha Sivaprasad, David H Steel, Tien Yin Wong, Charlie C Wykoff, Varun Chaudhary

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

João Pedro Lima *Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Dena Zeraatkar *Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Marah Al MasriDepartment of Surgery, McMaster University, Hamilton, ON, Canada.
Sobha SivaprasadNIHR Moorfields Biomedical Research Centre, Moorfields Eye Hospital, London, UK.
David H SteelSunderland Eye Infirmary, Queen Alexandra Road, Sunderland, UK.ORCID http://orcid.org/0000-0001-8734-3089
Tien Yin WongBeijing Visual Science and Translational Eye Research Institute, School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua Medicine, Tsinghua University, Beijing, China.ORCID http://orcid.org/0000-0002-8448-1264
Charlie C WykoffRetina Consultants of Texas, Houston, Texas, Blanton Eye Institute, Houston Methodist Hospital, Houston, TX, USA.ORCID http://orcid.org/0000-0001-7756-5091
Varun ChaudharyDepartment of Surgery, McMaster University, Hamilton, ON, Canada. vchaudh@mcmaster.ca.ORCID http://orcid.org/0000-0002-9988-4146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe World Health Organization estimates that 2.2 billion people worldwide suffer from vision impairment, representing an annual productivity loss of US$411 billion. Meanwhile, ophthalmology advances at a fast-moving pace. As in every discipline, optimal ophthalmologic care depends on trustworthy clinical practice guidelines that promote patient-centred care and support consistent, evidence-informed decision-making. Existing guidelines, however, may not always be up to date and their adherence to internationally accepted standards for trustworthy development is variable.

methodsWe describe OphthoEvidence, a model for producing rigorous clinical practice guidelines supported by systematic reviews and aligned with international trustworthy standards. Panels (8-14 stakeholders) including clinicians, patients, caregivers, researchers, and health-system decision makers will use the GRADE Evidence-to-Decision framework to formulate recommendations. A parallel Evidence Synthesis Team will conduct systematic reviews that will help panel members move from evidence to final recommendations.

conclusionOphthoEvidence will serve as an implementation model for the development of clinical practice guidelines in ophthalmology, adhering to international standards that ensure trustworthiness, transparency, and reproducibility while proposing a framework for other research groups and regulatory bodies.

Indexed as

OphthalmologyPractice Guidelines as TopicEvidence-Based MedicineHumans

Identifiers

PMID42082614
PMCPMC13342439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.