Evidence map›Paper›PMID 42082165›Full record

ArticleAnalytical chemistry2026

Circulating Tumor DNA Monitoring in Patients with Uveal Melanoma Using Mutation-Agnostic Multiplex Drop-Off ddPCR Assays.

Aurore Rampanou, Manuel Rodrigues, François-Clément Bidard, Nathalie Cassoux, Alexandre Matet, Anne Vincent-Salomon, Emmanuelle Jeannot, Ivan Bieche, Sergio Roman-Roman, Marc-Henri Stern and 1 more

Abstract read
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In one paragraph

Article in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aurore RampanouCirculating Tumor Biomarkers Laboratory, Inserm CIC 2501, Department of Translational Research, Institut Curie, Paris 75005, France.
Manuel RodriguesInserm U1339 CNRS UMR3666, DNA Repair and Uveal Melanoma (D.R.U.M.) Team, Institut Curie, PSL Research University, Paris 75005, France.
François-Clément BidardCirculating Tumor Biomarkers Laboratory, Inserm CIC 2501, Department of Translational Research, Institut Curie, Paris 75005, France.
Nathalie CassouxOcular Oncology Department, Institut Curie, Paris 75005, France.
Alexandre MatetOcular Oncology Department, Institut Curie, Paris 75005, France.
Anne Vincent-SalomonDepartment of Pathology, Institut Curie, PSL Research University, Paris 75005, France.
Emmanuelle JeannotDepartment of Pathology, Institut Curie, PSL Research University, Paris 75005, France.
Ivan BiecheDepartment of Genetics, Institut Curie, PSL Research University, Paris 75005, France.
Sergio Roman-RomanDepartment of Translational Research, Institut Curie, PSL Research University, Paris 75005, France.
Marc-Henri SternInserm U1339 CNRS UMR3666, DNA Repair and Uveal Melanoma (D.R.U.M.) Team, Institut Curie, PSL Research University, Paris 75005, France.
Shufang RenaultCirculating Tumor Biomarkers Laboratory, Inserm CIC 2501, Department of Translational Research, Institut Curie, Paris 75005, France.ORCID 0000-0001-9234-1002

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address the limitations of existing approaches─targeted next-generation sequencing (NGS) and simplex droplet digital PCR (ddPCR) assays─for circulating tumor DNA (ctDNA) detection in uveal melanoma (UM), we developed and validated mutation-agnostic multiplex drop-off ddPCR assays at the targeted loci as a novel strategy. Two multiplex drop-off ddPCR assays covering hotspot mutations in

Indexed as

Circulating Tumor DNAMelanomaMultiplex Polymerase Chain ReactionUveal NeoplasmsHumansMutationPolymerase Chain ReactionUveal MelanomaCirculating Tumor DNA

Identifiers

PMID42082165
PMCPMC13191726

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.