Evidence map›Paper›PMID 42081799›Full record

ArticleJMIR research protocols2026

Evaluating the Efficacy of Marma Therapy for Pain in Lumbar Disc Herniation With Radiculopathy: Protocol for a Randomized Controlled Trial.

Pallavi Mundada, Sunil Kumar Joshi, Shruti Khanduri, Tarun Kumar, Varsha Saxena, Disha Garg, Vinod Kumar Lavaniya, Rakesh Narayanan V, Bidhan Mahajon, Bhogavalli Chandra Sekhara Rao and 1 more

Abstract readClinical Trial Protocol
In one paragraph

Article in JMIR research protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pallavi MundadaCentral Council for Research in Ayurvedic Science, New Delhi, Delhi, India.ORCID 0000-0003-3326-2165
Sunil Kumar JoshiFaculty of Ayurveda, Uttarakhand Ayurved University, Dehradun, Uttarakhand, India.
Shruti KhanduriCentral Council for Research in Ayurvedic Science, New Delhi, Delhi, India.ORCID 0000-0001-6310-6505
Tarun KumarRegional Ayurveda Research Institute, Central Council for Research in Ayurvedic Science, Village Thapla P.O. Box 263645, Ganiyadholi, Ranikhet, Almora, Uttarakhand, India, 91 8851724923.ORCID 0000-0002-2324-0520
Varsha SaxenaFaculty of Ayurveda, Uttarakhand Ayurved University, Dehradun, Uttarakhand, India.ORCID 0000-0001-6457-4298
Disha GargCentral Council for Research in Ayurvedic Science, New Delhi, Delhi, India.ORCID 0000-0002-6265-8153
Vinod Kumar LavaniyaCentral Council for Research in Ayurvedic Science, New Delhi, Delhi, India.ORCID 0009-0003-7201-5818
Rakesh Narayanan VCentral Council for Research in Ayurvedic Science, New Delhi, Delhi, India.ORCID 0000-0002-1714-0697
Bidhan MahajonCentral Council for Research in Ayurvedic Science, New Delhi, Delhi, India.ORCID 0000-0002-9685-5788
Bhogavalli Chandra Sekhara RaoCentral Council for Research in Ayurvedic Science, New Delhi, Delhi, India.ORCID 0000-0001-5408-3225
Narayanam SrikanthCentral Council for Research in Ayurvedic Science, New Delhi, Delhi, India.ORCID 0000-0002-3976-4978

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Marma therapy, a traditional Ayurvedic practice, involves the precise stimulation of marmas (vital points that regulate prana [vital energy]) and alleviates musculoskeletal pain and dysfunction. While historical texts describe marma's role in pain relief, no randomized controlled trials have evaluated its efficacy and safety in lumbar disc herniation (LDH)-related radiculopathy. Objective: This study aims to explore the efficacy and safety of marma therapy in a commonly occurring painful condition, namely, radiculopathy due to LDH. Methods: Selected patients with LDH and radiculopathy are randomized into 2 groups using a computer-generated random number sequence. The participants in group 1 (the trial arm) are treated with marma therapy for 4 weeks, and those in group 2 (the control arm) receive physiotherapy for 4 weeks. All the participants in both groups are given an oral medicine, trayodashanga guggulu, an Ayurvedic formulation, for 12 weeks. Results: As of November 2025, a total of 90 patients have been enrolled in both groups. Data analysis is ongoing. The study will be reported following standard guidelines for reporting randomized controlled trials. Clinical trial results will be disseminated through conferences and publication in a peer-reviewed scientific journal. Conclusions: Marma therapy, if proven effective and safe in pain management, can improve the quality of life of patients with LDH. This protocol can be useful in designing large-scale studies to establish this noninvasive and safe treatment as an alternative modality for the management of neurological pain, such as radiculopathy.

Indexed as

Intervertebral Disc DisplacementMedicine, AyurvedicPain ManagementRadiculopathyAdultFemaleHumansLumbar VertebraeMaleMiddle AgedRandomized Controlled Trials as TopicTreatment OutcomeAyurvedalow-back painlumbar disc herniationmarma therapyradiculopathy

Identifiers

PMID42081799
PMCPMC13138787

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.