Evidence map›Paper›PMID 42081726›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Regulation of antiviral and antitumor immunity by the

Yoo Jane Han, Jing Zhang, Maryam Shariff, Sulin Wu, Galina Khramtsova, Long Chi Nguyen, Daniel S Peiffer, Nansheng Li, Anna Lewicka, Matthew Moore and 2 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. BRCA1P1 immunotherapy requires pseudogene-aware transcriptomics.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Reply to Chi et al.: DefiningProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yoo Jane HanSection of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637.ORCID 0000-0002-7465-2680
Jing ZhangSection of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637.ORCID 0009-0003-3332-8571
Maryam ShariffSection of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637.ORCID 0009-0001-9704-1882
Sulin WuSection of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637.
Galina KhramtsovaSection of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637.
Long Chi NguyenBen May Department for Cancer Research, University of Chicago, Chicago, IL 60637.
Daniel S PeifferSection of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637.
Nansheng LiDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637.
Anna LewickaDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637.
Matthew MooreDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637.
Joseph A PiccirilliDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637.ORCID 0000-0002-0541-6270
Olufunmilayo I OlopadeSection of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637.ORCID 0000-0002-9936-1599

Funding

UChicago Interdisciplinary Cancer Health Disparities SPOREP20CA233307 · NCI · UNIVERSITY OF CHICAGO · PI GODLEY, LUCY ANN · 2018 to 2020
$3.4M
Etiology and Genomics of Breast Cancer Progression in Women of African AncestryR01MD013452 · NIMHD · UNIVERSITY OF CHICAGO · PI HUO, DEZHENG, OLOPADE, OLUFUNMILAYO F. · 2019 to 2023
$2.8M
Breast Cancer Research Foundation (BCRF) BCRF-20-071HHS | NIH | National Cancer Institute (NCI) P20CA233307HHS | NIH | National Cancer Institute (NCI) R01MD013452NIMHD NIH HHS R01 MD013452
6 · The paper itself

Abstract

Pseudogenes have been regarded as nonfunctional byproducts of evolutionary processes. However, emerging evidence indicates that pseudogenes perform diverse biological roles in human physiology and pathology. We identified the

Indexed as

BRCA1 ProteinBreast NeoplasmsPseudogenesAnimalsApoptosisCell Line, TumorFemaleGene Expression Regulation, NeoplasticHumansMiceRibosomal ProteinsBRCA1 ProteinBRCA1 protein, humanRibosomal Proteinsantitumor immunityantiviral immune responseBRCA1P1circular RNApseudogene

Identifiers

PMID42081726
PMCPMC13167737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.