Evidence map›Paper›PMID 42081520›Full record

ArticlePloS one2026

Association between serum platelet level and dermatitis rash: Results from the China Health and Nutrition Survey.

Yue Jiang, Ding Li, Xiaojie Ding, Zhan Zhang, Xiaoxuan Ma, Haotian Xu, Guangyuan Cheng, Ying Zhang, Yi Ru, Ying Luo and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yue JiangDepartment of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Ding LiDepartment of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xiaojie DingDepartment of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhan ZhangDepartment of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xiaoxuan MaDepartment of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Haotian XuShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, China.
Guangyuan ChengShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, China.
Ying ZhangShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, China.
Yi RuShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, China.
Ying LuoDepartment of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wencheng JiangShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, China.
Ruiping WangShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, China.
Bin LiInstitute of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yue LuoShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, China.
Jiankun SongShanghai Skin Disease Hospital, Institute of Dermatology, School of Medicine, Tongji University, Shanghai, China.ORCID https://orcid.org/0000-0002-2546-5694

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermatitis rash (DR), a prevalent inflammatory skin disorder marked by erythema, pruritus, and scaling, poses diagnostic challenges due to overlapping phenotypes with atopic dermatitis and psoriasis. This study examines the relationship between serum platelet (PLT) levels and DR, as the PLT-DR link remains unknown. We used the China Health and Nutrition Survey (CHNS) database, 7,337 participants (172 DR cases, 7,165 controls) were analyzed. Baseline characteristics were compared via weighted chi-square tests. Multifactor regression models and weighted logistic regression assessed the PLT-DR relationship, while restricted cubic splines (RCS) explored nonlinear associations. The impact of age and sex was also evaluated. We found PLT levels significantly reduced DR risk (model 1: odds ratios (OR) = 0.9974 [95% confidence intervals (CI) = 0.9951-0.9998], P = 0.0316; model 2: OR = 0.9976 [95% CI = 0.9953-0.9999], P = 0.0490; model 3: OR = 0.9975 [95% CI = 0.9950-0.9999], P = 0.0398). Covariates such as previous smoking and rural residency were significantly associated with DR. Nonlinear models and risk stratification confirmed these findings, with female sex moderating the PLT-DR relationship. This elucidates that higher PLT levels may independently lower DR risk, suggesting diagnostic potential. PLT thresholds may enhance risk prediction models, aiding early intervention in high-risk populations.

Indexed as

Blood PlateletsDermatitis, AtopicExanthemaAdultCase-Control StudiesChinaFemaleHumansMaleMiddle AgedNutrition SurveysPlatelet CountRisk Factors

Identifiers

PMID42081520
PMCPMC13138638

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.