Evidence map›Paper›PMID 42081289›Full record

Trial reportMedicine and science in sports and exercise2026

Postural Instability Is Greater in Men with Type 2 Diabetes after Exertional Heat Stress.

Jericho Wee, Stesha Low, Xiang Ren Tan, Melvin Khee Shing Leow, Johan G Eriksson, Jason Kai Wei Lee

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine and science in sports and exercise, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jericho WeeHuman Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, SINGAPORE.
Stesha LowHuman Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, SINGAPORE.
Xiang Ren TanHuman Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, SINGAPORE.
Melvin Khee Shing LeowHuman Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, SINGAPORE.
Johan G ErikssonHuman Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, SINGAPORE.
Jason Kai Wei LeeHuman Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, SINGAPORE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIndividuals with type 2 diabetes (T2D) face a greater risk of heat-related illness during exercise compared to healthy counterparts. Here, we examined how T2D affects thermoregulation and postexercise postural sway in cool and warm-humid environments.

methodsMiddle-aged men with ( n = 15, age: 58 ± 5 yr, : 31 ± 6 mL · kg -1 · min -1 ) and without T2D (CON) ( n = 15, age: 58 ± 4 yr, : 34 ± 6 mL · kg -1 · min -1 ) walked for an hour at 6.0 W · kg -1 in 22°C, 50%RH (COOL) and 32°C, 70%RH (WARM) in a randomized counterbalanced crossover design. Gastrointestinal temperature (T gi ), skin temperatures (T sk ), heart rate, and whole-body sweat rate were assessed in this study. Postural balance (i.e., center of pressure [COP] excursions), handgrip strength and five-time sit-to-stand performance were assessed pre- and postexercise.

resultsMen with T2D showed greater increase in postural instability, particularly when balancing on an unstable surface after WARM compared to COOL, despite similar postexercise T gi , T sk , HR, and whole-body sweat rate between groups. Anteroposterior COP (WARM > COOL: +9 mm [95% CI: 3-15 mm], d = 0.86, P = 0.037); total COP excursion (WARM > COOL: +126 mm [95% CI: 48-204 mm], d = 0.87, P = 0.018), and COP mean velocity (WARM > COOL: +5 mm · s -1 [95% CI: 2-7 mm · s -1 ], d = 1.49, P = 0.003) were increased only in men with T2D in WARM.

conclusionsPostural instability increased only in middle-aged men with T2D in humid heat, despite comparable thermoregulatory responses with age-matched men without T2D. This may be attributed to T2D-associated impairments (e.g., altered hemodynamics and/or vibrotactile sensitivity) which can lead to an increased fall risk during or after exercise in the heat.

Indexed as

Diabetes Mellitus, Type 2Heat Stress DisordersPhysical ExertionPostural BalanceBody TemperatureBody Temperature RegulationCross-Over StudiesHand StrengthHeart RateHot TemperatureHumansHumidityMaleMiddle AgedSkin TemperatureSweatingAGINGFALL RISKHYPERTHERMIAPOSTURAL BALANCETHERMOREGULATION

Identifiers

PMID42081289
PMCPMC13446912

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.