Evidence map›Paper›PMID 42080905›Full record

ArticleAnalytical and bioanalytical chemistry2026

Dual-mode electrochemical and colorimetric biosensing platform using MOF-stabilized iron nanoclusters for ultrasensitive detection of Pseudomonas aeruginosa.

Bohao Zhang, Pengcheng Liu, Jiyao Zhang, Xi Chen, Zhenggang Chen, Qingyin Zheng, Peng Ma, Chen Wang, Xing-Hua Xia, Wen-Chao Hu

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Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bohao Zhang *School of Special Education and Rehabilitation, School of Stomatology, Binzhou Medical University, Yantai, 264003, China.
Pengcheng Liu *School of Special Education and Rehabilitation, School of Stomatology, Binzhou Medical University, Yantai, 264003, China.
Jiyao ZhangSchool of Special Education and Rehabilitation, School of Stomatology, Binzhou Medical University, Yantai, 264003, China.
Xi ChenSchool of Special Education and Rehabilitation, School of Stomatology, Binzhou Medical University, Yantai, 264003, China.
Zhenggang ChenSchool of Special Education and Rehabilitation, School of Stomatology, Binzhou Medical University, Yantai, 264003, China.
Qingyin ZhengSchool of Special Education and Rehabilitation, School of Stomatology, Binzhou Medical University, Yantai, 264003, China.
Peng MaSchool of Special Education and Rehabilitation, School of Stomatology, Binzhou Medical University, Yantai, 264003, China.
Chen WangSchool of Chemistry and Materials Science, Nanjing Normal University, Nanjing, 210023, China.
Xing-Hua XiaState Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, China.
Wen-Chao HuSchool of Special Education and Rehabilitation, School of Stomatology, Binzhou Medical University, Yantai, 264003, China. huwenchao@bzmc.edu.cn.

Funding

National Natural Science Foundation of China 22022412National Natural Science Foundation of China 22204006National Natural Science Foundation of China 22274076National Natural Science Foundation of China 822052412the Education Department of Shandong Province no. 2023KJ258
6 · The paper itself

Abstract

Pseudomonas aeruginosa is a prevalent multidrug-resistant pathogen responsible for severe infections. Rapid, ultrasensitive, and selective detection of this bacterium is essential for effective clinical diagnostics and infection control. Here, we report a novel dual-mode biosensing platform based on two-dimensional metal-organic framework-stabilized iron nanoclusters (MOF-Fe NCs) for the simultaneous electrochemical and colorimetric detection of P. aeruginosa. The MOF-Fe NCs display synergistic properties, including exceptional electrocatalytic activity and robust peroxidase-like (POD-like) behavior. Specific capture of the target bacteria by a surface-immobilized F23 aptamer modulates electrochemical signaling and suppresses the POD-like activity for colorimetric readout. The dual-mode bioassay achieves a broad detection range from 10

Indexed as

Biosensing TechniquesColorimetryElectrochemical TechniquesIronMetal NanoparticlesMetal-Organic FrameworksPseudomonas aeruginosaLimit of DetectionIronMetal-Organic FrameworksDual-mode biosensorElectrochemical and colorimetric detectionIron nanoclustersPseudomonas aeruginosaTwo-dimensional metal–organic frameworks

Identifiers

PMID42080905

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.