Evidence map›Paper›PMID 42080774›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2026

Correlates of Viral Suppression in Adolescents With HIV Taking Antiretroviral Therapy in Mozambique: Results of a Multicenter Cross-Sectional Survey.

Joana Falcao, Elaine J Abrams, Frédérique Chammartin, Aleny Couto, Allison Zerbe, Eduarda Pimentel De Gusmao, Kelvin Manuel, Niklaus D Labhardt

Registry-linked trialAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04930367 (CombinADO), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04930367 nacompletednot on this map

CombinADO: a Cluster-randomized Controlled Trial to Compare the Efficacy, Uptake, Feasibility and Acceptability of the CombinADO Strategy Versus Optimized Standard of Care on Viral Suppression, ART Adherence and Retention in HIV Care Among Adolescents and Young Adults Living with HIV Ages 10-24yrs in Nampula Province, Mozambique

TypeinterventionalSponsorColumbia UniversityRan2021 to 2023Enrolled1,715ConditionsHIVArmsRadio Ads, Community Sensitization Campaign, Informational Posters, Motivation Walls, Pill Container
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joana FalcaoICAP at Columbia University, Mailman School of Public Health, Maputo, Mozambique; Clinical Epidemiology, Department of Clinical Research, University and University Hospital Basel, Basel, Switzerland. Electronic address: Joana.falcao@usb.ch.
Elaine J AbramsICAP at Columbia University, Mailman School of Public Health, New York, New York; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York; Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York.
Frédérique ChammartinClinical Epidemiology, Department of Clinical Research, University and University Hospital Basel, Basel, Switzerland.
Aleny CoutoNational STI, HIV/AIDS Control Program, Maputo, Mozambique.
Allison ZerbeICAP at Columbia University, Mailman School of Public Health, New York, New York.
Eduarda Pimentel De GusmaoICAP at Columbia University, Mailman School of Public Health, Maputo, Mozambique.
Kelvin ManuelICAP at Columbia University, Mailman School of Public Health, Maputo, Mozambique.
Niklaus D LabhardtClinical Epidemiology, Department of Clinical Research, University and University Hospital Basel, Basel, Switzerland.

Funding

CombinADO: a combination intervention strategy to improve health outcomes for adolescents living with HIVUH3HD096926 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ABRAMS, ELAINE JANINE · 2020 to 2022
$4.1M
NICHD NIH HHS UH3 HD096926
6 · The paper itself

Abstract

purposeAdolescents living with HIV (ALHIV) have poorer outcomes on antiretroviral therapy (ART) than adults. We assessed correlates of viral suppression (VS) among ALHIV, aged 15-19 years, in Mozambique.

methodsThis is a nested analysis within the CombinADO trial (NCT04930367), a cluster randomized trial assessing the effectiveness of a multilevel health services intervention to improve VS (HIV RNA <50 copies/mL) among ALHIV. After 12 months of intervention implementation, ALHIV at 12 health facilities were approached for enrolment into a postintervention assessment that included surveys and a blood draw for viral load (VL) measurement. Multivariable logistic regression reporting adjusted odds ratios (aORs) was used to quantify the association of different factors with VS. Data were collected between November 2022 and July 2023.

resultsOf 544 ALHIV 15-19 years (72% female) included in this analysis, 300 (55%) had VS. ALHIV who understood their latest VL result were more likely to have VS (aOR = 1.59, 95% confidence interval [CI] 1.05-2.42). VS was lower among ALHIV who had moderate and high levels of internalized stigma (aOR = .45, 95% CI .21-.96 and aOR = 0.38, 95% CI .17-.88, respectively). DISCUSSION: Reducing internalized stigma and improving understanding of VL results may contribute to improving VS among ALHIV in Mozambique. These findings underscore the urgent need for adolescent tailored HIV care in Mozambique.

Indexed as

Anti-HIV AgentsHIV InfectionsViral LoadAdolescentCross-Sectional StudiesFemaleHumansMaleMozambiqueYoung AdultAnti-HIV AgentsAdolescentsARTHIVHIV viral suppressionMozambique

Identifiers

PMID42080774
PMCPMC13509033

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Registered trials

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