Evidence map›Paper›PMID 42080560›Full record

ArticleAntimicrobial agents and chemotherapy2026

Clinical failure of an extended-pulsed fidaxomicin regimen associated with emergence of a

Claire E Kaple, Sarah N Redmond, Jennifer L Cadnum, Bryan Hausman, Munok Hwang, Hosoon Choi, Piyali Chatterjee, Chetan Jinadatha, Curtis J Donskey

Abstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A sensitive and reduced-cost culture medium for recovery ofJournal of clinical microbiology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Claire E Kaple *Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Sarah N Redmond *Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Jennifer L CadnumResearch Service, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
Bryan HausmanResearch Service, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
Munok HwangDepartment of Research, Central Texas Veterans Healthcare System, Temple, Texas, USA.
Hosoon ChoiDepartment of Research, Central Texas Veterans Healthcare System, Temple, Texas, USA.ORCID 0000-0002-8272-9828
Piyali ChatterjeeDepartment of Research, Central Texas Veterans Healthcare System, Temple, Texas, USA.
Chetan JinadathaDepartment of Medicine, Central Texas Veterans Healthcare System, Temple, Texas, USA.ORCID 0000-0002-3916-952X
Curtis J DonskeyDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID 0000-0003-0990-4498

Funding

BLRD VA I01 BX006885U.S. Department of Veterans AffairsU.S. Department of Veterans Affairs 1I01BX006885-01A1
6 · The paper itself

Abstract

The clinical significance of

Indexed as

AminoglycosidesAnti-Bacterial AgentsClostridioides difficileClostridium InfectionsAnimalsBacterial ProteinsDrug Resistance, BacterialFidaxomicinHumansMaleMiceMicrobial Sensitivity TestsTreatment FailureAminoglycosidesAnti-Bacterial AgentsBacterial ProteinsFidaxomicinclinical failureClostridioides difficilefidaxomicinresistance

Identifiers

PMID42080560
PMCPMC13436074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.