Evidence map›Paper›PMID 42080483›Full record

ReviewEthics & human research

Human Research Protections during Emergencies: An Integrative Review.

Lauren M Sauer, Megan K Singleton, Andrew Stolbach, Jonathan M Links, Beth Resnick, Lainie Rutkow

Abstract readReview
In one paragraph

Review in Ethics & human research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lauren M SauerAssociate professor in the Department of Environmental, Agricultural, and Occupational Health at the College of Public Health at the University of Nebraska Medical Center.
Megan K SingletonAssociate dean for human research protection and a director of the Human Research Protections Program at Johns Hopkins University School of Medicine.
Andrew StolbachAssociate professor in the Department of Emergency Medicine at Johns Hopkins University School of Medicine.
Jonathan M LinksProfessor and vice provost and chief risk officer at Johns Hopkins University.
Beth ResnickPractice professor in the Department of Health Policy and Management and assistant dean for practice and training at the Bloomberg School of Public Health at Johns Hopkins University.
Lainie RutkowProfessor in the Department of Health Policy and Management at the Bloomberg School of Public Health at Johns Hopkins University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing frequency and severity of various types of societal and humanitarian emergencies-e.g., infectious disease outbreaks and natural disasters-creates unique challenges for conducting human subjects research in these settings. These challenges include regulatory review complexities, maintaining research rigor while increasing efficiency, protecting vulnerable populations, and managing risks. Despite these obstacles, research is critical for improving responses to societal and humanitarian emergencies and protecting public health. Our integrative review examines the use of emergency or rapid response review boards, including ethics reviews and institutional review boards (IRBs), in emergency contexts. An integrative literature search addressed rapid emergency human subjects research reviews across disasters, infectious disease emergencies, humanitarian crises, and public health emergencies. Articles were selected based on pre-defined criteria, including empirical research, operational action, and theoretical discussion. Data were abstracted and synthesized to identify common themes, gaps, and recommendations. Findings underscore the need for robust IRB support before and during emergencies. Recommendations include pre-approved protocols, enhanced training, and increased funding and resources for emergency IRB support. Future research should systematically implement these concepts and assess their effectiveness across diverse emergency contexts.

Indexed as

EmergenciesEthics Committees, ResearchHuman ExperimentationAltruismDisastersDisease OutbreaksHumansPublic Healthhumanitarian emergencieshuman research ethicsinfectious disease outbreaksinstitutional review boards (IRBs)natural disasterspublic health emergencies

Identifiers

PMID42080483
PMCPMC13137931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.